Botulinum toxin A in the management of focal muscle overactivity in children with cerebral palsy.

Botulinum toxin A in the management of focal muscle overactivity in children with cerebral palsy. Research Abstract Details 

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Botulinum toxin A in the management of focal muscle overactivity in children with cerebral palsy. Abstract Text:

Noula Gibson,H Kerr Graham,Sarah Love,Noula Gibson,H Kerr Graham,Sarah Love,

Cerebral palsy comprises a heterogenous group of neurological disorders representing a continuum of pathologies and clinical phenotypes. Although cerebral palsy is not a focal disorder, it is appropriate to treat identified focal problems as long as the intervention is goal directed. This paper reviews principles of managing muscle imbalance in the growing, changing child using a range of complementary, carefully timed intervention options. Over the past two decades these options have increasingly included intramuscular injection of botulinum toxin-A to manage focal spasticity and dystonia. The predictable movement patterns and postures characteristic of spasticity enable a systematic clinical rationale to be developed to determine the role of botulinum toxin-A to manage the spasticity and subsequently improve function. The management of dystonia with botulinum toxin-A is more complex, particularly when spasticity and dystonia are present in combination. An active therapy programme remains central to the management of movement problems in the child with cerebral palsy, including task-specific motor training, maintenance of muscle lengths, and improved muscle strength, aiming to achieve carry over improvements that persist beyond the pharmacological effects of the botulinum toxin-A. A series of case examples are presented to highlight the role of botulinum toxin-A in the overall management of the child with focal muscle hyperactivity.

Botulinum toxin A in the management of focal muscle overactivity in children with cerebral palsy. Publishing Authors By Initials

N Gibson,HK Graham,S Love,N Gibson,HK Graham,S Love,

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Botulinum toxin A in the management of focal muscle overactivity in children with cerebral palsy. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Disability and rehabilitation

VOLUME: 29

Page Numbers: 1813-22

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ISSN: 0963-8288

DAY: 15

MONTH: Dec

YEAR: 2007

Botulinum toxin A in the management of focal muscle overactivity in children with cerebral palsy. Information

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LANGUAGE: eng

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AFFILIATION: Princess Margaret Hospital, Perth.

Country: England

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MEDLINETA: Disabil Rehabil

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