Bone marrow edema-like lesions change in volume in the majority of patients with osteoarthritis; associations with clinical features.

Bone marrow edema-like lesions change in volume in the majority of patients with osteoarthritis; associations with clinical features. Research Abstract Details 

Research Abstract Table of Contents

Jump to the:

Bone marrow edema-like lesions change in volume in the majority of patients with osteoarthritis; associations with clinical features. Abstract Text:

Peter R Kornaat,Margreet Kloppenburg,Ruby Sharma,Stella A Botha-Scheepers,Marie-Pierre Hellio Le Graverand,L Napoleon J E M Coene,Johan L Bloem,Iain Watt,Peter R Kornaat,Margreet Kloppenburg,Ruby Sharma,Stella A Botha-Scheepers,Marie-Pierre Hellio Le Graverand,L Napoleon J E M Coene,Johan L Bloem,Iain Watt,

It has been suggested that bone marrow edema-like (BME) lesions in the knee are associated with progression of osteoarthritis (OA). The purpose of our study in patients with OA was to evaluate prospectively changes of BME lesions over 2 years and their relationship with clinical features. Magnetic resonance (MR) images of the knee were obtained from 182 patients (20% male; aged 43-76 years; mean age 59 years) who had been diagnosed with familial symptomatic OA at multiple joint sites. MR images were made at baseline and at 2 years follow-up. BME lesions in 2 years were associated with clinical features assessed by Western Ontario and McMaster Universities Osteoarthritis (WOMAC) scores. A total of 327 BME lesions were recorded. Total size of BME lesions changed in 90 patients (66%). Size of individual lesions changed in 147 foci (45%): new lesions appeared in 69 (21%), existing lesions disappeared in 32 (10%), increased in size in 26 (8%) and decreased in size in 20 (6%) lesions. Increase or decrease of BME lesions, over a 2-year time period, was not associated with severity of WOMAC scores. BME lesions fluctuated in the majority of patients with OA over a 2-year time period. These changes were not associated with severity of WOMAC scores at the study end point.

Bone marrow edema-like lesions change in volume in the majority of patients with osteoarthritis; associations with clinical features. Publishing Authors By Initials

PR Kornaat,M Kloppenburg,R Sharma,SA Botha-Scheepers,MP Le Graverand,LN Coene,JL Bloem,I Watt,PR Kornaat,M Kloppenburg,R Sharma,SA Botha-Scheepers,MP Le Graverand,LN Coene,JL Bloem,I Watt,

For similar abstracts research abstracts see: abstracts research

PUBMED ID PMID:

MEDLINE DATE:

Bone marrow edema-like lesions change in volume in the majority of patients with osteoarthritis; associations with clinical features. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: European radiology

VOLUME: 17

Page Numbers: 3073-8

Journal Abbreviation:

ISSN: 0938-7994

DAY: 7

MONTH: 09

YEAR: 2007

Bone marrow edema-like lesions change in volume in the majority of patients with osteoarthritis; associations with clinical features. Information

Number of References:

LANGUAGE: eng

NlmUniqueID: 9114774

Bone marrow edema-like lesions change in volume in the majority of patients with osteoarthritis; associations with clinical features. Keywords Mesh Terms:

KEYWORDS:

MESH TERMS:

Chemical & Substance for Abstract: Bone marrow edema-like lesions change in volume in the majority of patients with osteoarthritis; associations with clinical features. Information

Substance Name:

Registry Number:

Grant and Affiliation Information for Bone marrow edema-like lesions change in volume in the majority of patients with osteoarthritis; associations with clinical features.

AFFILIATION: Department of Radiology, Leiden University Medical Center, Albinusdreef 2, 2333 ZA, Leiden, The Netherlands, P.R.Kornaat@lumc.nl.

Country: Germany

AGENCY:

GRANT:

ACRONYM:

MEDLINETA: Eur Radiol

REFSOURCE:

DATABASENAME:

ACCESSION NUMBER:

Number Hits: 0

Bone marrow edema-like lesions change in volume in the majority of patients with osteoarthritis; associations with clinical features Related Publications

• A simple benzidine test for occult blood in feces.
• Adipocyte triglyceride lipase expression in human obesity.
• Anaerobic iron deposition into horse spleen, recombinant human heavy and light and bacteria ferritins by large oxidants.
• Bone marrow edema-like lesions change in volume in the majority of patients with osteoarthritis; associations with clinical features.
• Brian harold bartlett.
• Changes in photosynthetic rates and gene expression of leaves during a source-sink perturbation in sugarcane.
• Conflicts between biodiversity conservation and human activities in the central and eastern European countries.
• Curare-modified electric convulsion therapy in cases with physical disease.
• Difference in work-related violence by nurse license type.
• Embryos and pseudoembryos: parthenotes, reprogrammed oocytes and headless clones.
• Expression of Notch pathway genes in mammalian epidermis and modulation by beta-catenin.
• First 6 months of the National Health Service.
• Fly control and the acute diarrheal diseases.
• Intravenous procaine therapy.
• Introduction of Hib vaccine into national immunization programmes: a descriptive analysis of global trends.
• Jagged 1 is a beta-catenin target gene required for ectopic hair follicle formation in adult epidermis.
• Lipids and fatty acids of important finfish: new data for nutrient tables.
• Mice deficient in involucrin, envoplakin, and periplakin have a defective epidermal barrier.
• Newer Procedures in Laboratory Diagnosis and Therapy in the Control of Bacillary Dysentery.
• Outbreak of Legionnaires' disease in West Fife: Review of environmental guidelines needed.
• Preservice and Inservice Preparation in Health of School Personnel-A Symposium: Role of the Department of Education and the Department of Health in the Inservice Preparation of Classroom Teachers, School Administrators, School Nurses, and School Physician
• Streamlining Hospital Techniques: Practical Implications of the Epidemiology of the Diarrheal diseases of the New-born.
• Strong corsets and pelvic congestion.
• Syntenin mediates Delta1-induced cohesiveness of epidermal stem cells in culture.
• The Acute Diarrheal Disorders.
• The KITS scheme.
• The RNA methyltransferase Misu (NSun2) mediates Myc-induced proliferation and is upregulated in tumors.
• The murine ortholog of the SHP-2 binding molecule, PZR accelerates cell migration on fibronectin and is expressed in early embryo formation.
• The role of blood services and regulatory bodies in stem cell transplantation.
• Viral hepatitis in the Arctic. A review from a Circumpolar Workshop on Viral hepatitis, ICCH13.