Bone marrow-derived stem cell therapy in ischemic heart disease.

Bone marrow-derived stem cell therapy in ischemic heart disease. Research Abstract Details 

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Bone marrow-derived stem cell therapy in ischemic heart disease. Abstract Text:

Hyun-Jai Cho,Juyong Lee,Andrea Wecker,Young-sup Yoon,

Since the first experiments of cell transplantation into the heart were performed in the early 1990s, the identification of adult stem cells has triggered attempts to regenerate damaged heart tissue by cellular transplantation. Until recently, a multitude of adult stem or progenitor cells from various tissues have been proposed to meet this end. Bone marrow in particular has emerged as the most promising source for stem and progenitor cells because, besides being the organ of hematopoietic maintenance, it contains a complex assortment of stem and progenitor cells. A large body of provocative experimental evidence for vascular and myocardial regeneration by these cells has generated further enthusiasm for their use. However, many questions remain unanswered in this new field of research regarding the therapeutic potential and the mechanisms responsible for the observed therapeutic effects. In this review, the authors discuss the therapeutic capacity of currently available representative bone marrow-derived stem and progenitor cells for treating ischemic heart diseases.

Bone marrow-derived stem cell therapy in ischemic heart disease. Publishing Authors By Initials

HJ Cho,J Lee,A Wecker,YS Yoon,

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Bone marrow-derived stem cell therapy in ischemic heart disease. Journal Published:

PUBLICATION TYPE: Review

Journal: Regenerative medicine

VOLUME: 1

Page Numbers: 337-45

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ISSN: 1746-076X

DAY: 3

MONTH: May

YEAR: 2006

Bone marrow-derived stem cell therapy in ischemic heart disease. Information

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LANGUAGE: eng

NlmUniqueID: 101278116

Bone marrow-derived stem cell therapy in ischemic heart disease. Keywords Mesh Terms:

KEYWORDS: Tissue Donors

MESH TERMS: physiology

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Grant and Affiliation Information for Bone marrow-derived stem cell therapy in ischemic heart disease.

AFFILIATION: Caritas St. Elizabeth's Medical Center, Division of Cardiovascular Research, Tufts University School of Medicine, Boston, Massachusetts 02135, USA.

Country: England

AGENCY: United States NHLBI

GRANT: HL079137

ACRONYM: HL

MEDLINETA: Regen Med

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