Bone and mineral metabolism in transient hyperphosphatasaemia.

Bone and mineral metabolism in transient hyperphosphatasaemia. Research Abstract Details 

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Bone and mineral metabolism in transient hyperphosphatasaemia. Abstract Text:

S Kutílek,M Bayer,J J St?pán,

Transient hyperphosphatasaemia (TH) is a benign disorder characterized by transient elevation of S-ALP activity not exceeding duration of 4 months in children under 5 years of age, with elevated activity of bone isoenzymes of ALP with no signs of bone or liver disease and variable unrelated symptoms. We observed 19 children with TH and in 3 patients with markedly elevated S-ALP activity we found increased excretion of urinary hydroxyproline, suggesting increased bone resorption followed by bone formation. In 3 children with history of TH, bone mineral density (BMD) was measured and found to be normal. Transient increased bone resorption followed by bone formation during the course of TH can not be ruled out, but this has no negative impact on BMD.

Bone and mineral metabolism in transient hyperphosphatasaemia. Publishing Authors By Initials

S Kutílek,M Bayer,JJ St?pán,

For similar inorganic chemicals: minerals research abstracts see: inorganic chemicals: minerals research

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Bone and mineral metabolism in transient hyperphosphatasaemia. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Acta Universitatis Carolinae. Medica

VOLUME: 40

Page Numbers: 47-51

Journal Abbreviation:

ISSN: 0001-7116

DAY: 20

MONTH: 02

YEAR: 1994

Bone and mineral metabolism in transient hyperphosphatasaemia. Information

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LANGUAGE: eng

NlmUniqueID: 2985169

Bone and mineral metabolism in transient hyperphosphatasaemia. Keywords Mesh Terms:

KEYWORDS: Minerals

MESH TERMS: metabolism

Chemical & Substance for Abstract: Bone and mineral metabolism in transient hyperphosphatasaemia. Information

Substance Name: Alkaline Phosphatase

Registry Number: EC 3.1.3.1

Grant and Affiliation Information for Bone and mineral metabolism in transient hyperphosphatasaemia.

AFFILIATION: Department of Pediatrics, 1st Medical Faculty, Charles University, Prague, Czech Republic.

Country: CZECH REPUBLIC

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MEDLINETA: Acta Univ Carol [Med] (Praha)

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