Bombyx Y-box protein BYB facilitates specific DNA interaction of various DNA binding proteins independently of the cold shock domain.

Bombyx Y-box protein BYB facilitates specific DNA interaction of various DNA binding proteins independently of the cold shock domain. Research Abstract Details 

Research Abstract Table of Contents

Jump to the:

Bombyx Y-box protein BYB facilitates specific DNA interaction of various DNA binding proteins independently of the cold shock domain. Abstract Text:

Shigeharu Takiya,Yoshinori Nishita,Susumu Ishikawa,Kaoru Ohno,Taka-aki Tamura,Yoshiaki Suzuki,

A new member of the Y-box protein family of the silkworm Bombyx mori (BYB) was co-purified with the fibroin gene enhancer-binding protein FMBP-1, and stimulated the binding of FMBP-1 to its cognate DNA element. However, the stimulatory effect was not specific to FMBP-1, BYB also enhancing the binding of mammalian transcription factors OTF2, SP1 and AP2 to their specific binding elements. Besides the above transcription regulatory factors, BYB facilitated the binding of basal transcription factor TBP, and enhanced transcription from the adenovirus 2 major late promoter in a reconstituted transcription system. Moreover, BYB stimulated the reactions of some restriction endonucleases under cold conditions. The C-terminal region of BYB was sufficient for these stimulatory effects, and the highly conserved cold shock domain (CSD) in the N-terminal region was dispensable. GST-pull down experiments showed that the C-terminal region could interact with DNA independently of the CSD. The above results suggest that the C-terminal region of BYB causes the active interaction of various DNA binding proteins with their targets. Such a function of the C-terminal region of BYB may partly explain the functional diversity of Y-box proteins.

Bombyx Y-box protein BYB facilitates specific DNA interaction of various DNA binding proteins independently of the cold shock domain. Publishing Authors By Initials

S Takiya,Y Nishita,S Ishikawa,K Ohno,TA Tamura,Y Suzuki,

For similar proteins: transcription factors research abstracts see: proteins: transcription factors research

PUBMED ID PMID:

MEDLINE DATE:

Bombyx Y-box protein BYB facilitates specific DNA interaction of various DNA binding proteins independently of the cold shock domain. Journal Published:

PUBLICATION TYPE: Research Support, Non-U.S. Gov

Journal: Journal of biochemistry

VOLUME: 135

Page Numbers: 683-93

Journal Abbreviation: J. Biochem.

ISSN: 0021-924X

DAY: 19

MONTH: Jun

YEAR: 2004

Bombyx Y-box protein BYB facilitates specific DNA interaction of various DNA binding proteins independently of the cold shock domain. Information

Number of References:

LANGUAGE: eng

NlmUniqueID: 376600

Bombyx Y-box protein BYB facilitates specific DNA interaction of various DNA binding proteins independently of the cold shock domain. Keywords Mesh Terms:

KEYWORDS: Transcription Factors

MESH TERMS: metabolism

Chemical & Substance for Abstract: Bombyx Y-box protein BYB facilitates specific DNA interaction of various DNA binding proteins independently of the cold shock domain. Information

Substance Name: DNA

Registry Number: 9007-49-2

Grant and Affiliation Information for Bombyx Y-box protein BYB facilitates specific DNA interaction of various DNA binding proteins independently of the cold shock domain.

AFFILIATION: Laboratory of Gene Function and Regulation, CAST, Hokkaido University, North 10, West 8, Kita-ku, Sapporo 060-0810, Japan. takiya@rmg.hokudai.ac.jp

Country: Japan

AGENCY:

GRANT:

ACRONYM:

MEDLINETA: J Biochem

REFSOURCE:

DATABASENAME:

ACCESSION NUMBER: AB098537

Number Hits: 0

Bombyx Y-box protein BYB facilitates specific DNA interaction of various DNA binding proteins independently of the cold shock domain Related Publications

• A uniformly cleaved epitaxically grown diamond crystal for synchrotron radiation.
• Absolute soft X-ray measurements using an ion chamber.
• Agmatine suppresses mesangial cell proliferation by modulating polyamine metabolism.
• Attention induces synchronization-based response gain in steady-state visual evoked potentials.
• Behavior of Medaka fish under distributed gravity.
• Branched-chain amino acid supplementation during the endoscopic injection sclerotherapy for esophageal varices may be useful for maintenance of nutritional status in patients with liver cirrhosis.
• Comprehensive genetic selection revealed essential bases in the peptidyl-transferase center.
• Cytokine production of CD8+ immune T cells but not of CD4+ T cells from Toxoplasma gondii-infected mice is polarized to a type 1 response following stimulation with tachyzoite-infected macrophages.
• Developmental capacity of bovine oocytes cryopreserved after maturation in vitro and of frozen-thawed bovine embryos derived from frozen mature oocytes.
• Developmental capacity of bovine oocytes frozen in different cryoprotectants.
• Effects of different lots of semen from the same bull on in vitro development of bovine oocytes fertilized in vitro.
• Effects of pressure on the phase transition of bilayers in liposomes. Influence of cholesterol and alpha-tocopherol.
• Elevated extracellular calcium stimulates secretion of bone morphogenetic protein 2 by a macrophage cell line.
• Expression of bHLH Transcription Factors and IGFs in the Non-sensory Patches, Olfactory Epithelium and Vomeronasal Organ.
• Fasting plasma ghrelin levels reflect malnutrition state in patients with liver cirrhosis.
• Hepatocyte-specific Pten-deficient mice as a novel model for nonalcoholic steatohepatitis and hepatocellular carcinoma.
• Hyperplasia and carcinomas in Pten-deficient mice and reduced PTEN protein in human bladder cancer patients.
• Improvement in cognitive function after radical excision of an anterior skull base meningioma - a report of 2 cases.
• Independent representation of parts and the relations between them: evidence from integrative agnosia.
• Prognosis-predicting equations using histological scores contribute to the choice of steroid therapy in IgA nephropathy: Multivariate analysis on 275 adult patients.
• Proteome analysis of glial cells treated by radiation or hydroperoxide.
• Relationship between progesterone and estradiol contents of follicular fluid and the morphological appearance of granulosa cells of follicles coexisting with corpora lutea in bovine ovaries.
• Safety of ablation of the sigmoid and transverse sinuses: an experimental study.
• Species specific differences in the ratio of short to long loop nephrons in the kidneys of laboratory rodents.
• Superovulation in the cow with a single intramuscular injection of FSH dissolved in polyvinylpyrrolidone.
• Synergism between a mycoreovirus and a hypovirus mediated by the papain-like protease p29 of the prototypic hypovirus CHV1-EP713.
• The A-site finger in 23 S rRNA acts as a functional attenuator for translocation.
• Viability of frozen-thawed bovine IVM/IVF embryos in relation to aging using various cryoprotectants.
• [High performance liquid chromatographic determination of reducing sugars in fruit juices with laser resonance Raman detection]
• [Selective extraction of organotin from biological sample by supercritical fluid extraction]