Bleomycin: effect on satellite DNA in mouse fibroblasts.

Bleomycin: effect on satellite DNA in mouse fibroblasts. Research Abstract Details 

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Bleomycin: effect on satellite DNA in mouse fibroblasts. Abstract Text:

The effect of Bleomycin on the semiconservative replication of mouse nuclear DNA has been studied. When asynchronously dividing mouse fibroblasts (L-cells) were grown in the presence of 5-bromodeoxyuridine (25 mg/l medium) for 18 h, three hybrid DNA bands with densities of 1.722, 1.752, and 1.761 kg/l appeared after caesium chloride density gradient centrifugation of nuclear DNA. In cells exposed to Bleomycin (100 mg/l) however, replication of satellite DNA is more strongly inhibited than is the replication of the main band DNA; preferentially the thymidinerich hybrid duplex at 1.761 kg/l could no longer be detected.

Bleomycin: effect on satellite DNA in mouse fibroblasts. Publishing Authors By Initials

For similar biochemical phenomena, metabolism, and nutrition: biochemical phenomena: nucleic acid renaturation research abstracts see: biochemical phenomena, metabolism, and nutrition: biochemical phenomena: nucleic acid renaturation research

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Bleomycin: effect on satellite DNA in mouse fibroblasts. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Zeitschrift für Krebsforschung und klinische Onkol

VOLUME: 92

Page Numbers: 309-13

Journal Abbreviation:

ISSN: 0084-5353

DAY: 30

MONTH: Oct

YEAR: 1978

Bleomycin: effect on satellite DNA in mouse fibroblasts. Information

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LANGUAGE: eng

NlmUniqueID: 1276653

Bleomycin: effect on satellite DNA in mouse fibroblasts. Keywords Mesh Terms:

KEYWORDS: Nucleic Acid Renaturation

MESH TERMS: drug effects

Chemical & Substance for Abstract: Bleomycin: effect on satellite DNA in mouse fibroblasts. Information

Substance Name: Bleomycin

Registry Number: 11056-06-7

Grant and Affiliation Information for Bleomycin: effect on satellite DNA in mouse fibroblasts.

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Country: GERMANY, WEST

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MEDLINETA: Z Krebsforsch Klin Onkol Cance

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