Birth characteristics and risk of neuroblastoma in young children.

Birth characteristics and risk of neuroblastoma in young children. Research Abstract Details 

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Birth characteristics and risk of neuroblastoma in young children. Abstract Text:

Kevin Y Urayama,Julie Von Behren,Peggy Reynolds,

The peak incidence of neuroblastoma during infancy suggests that certain prenatal or perinatal factors may be etiologically important. In this population-based study, California birth certificates were identified for 508 (86%) neuroblastoma cases diagnosed at less than 5 years of age between 1988 and 1997. For each case, two controls, matched on date of birth and gender, were randomly selected from the statewide birth registry. Results of multivariate analyses showed a reduced risk for children of Hispanic (odds ratio (OR) = 0.57, 95% confidence interval (CI): 0.43, 0.76) and "other" (OR = 0.56, 95% CI: 0.37, 0.85) race/ethnicity, compared with non-Hispanic Whites. Postterm/high birth weight delivery was associated with an increased risk of neuroblastoma compared with term/normal birth weight delivery among infants (OR = 6.99, 95% CI: 1.07, 45.55), while preterm birth appeared suggestive of a reduced risk among children 1-4 years of age. For children in this age group, the risk of neuroblastoma was elevated for cesarean delivery compared with vaginal delivery (OR = 1.72, 95% CI: 1.21, 2.47), and, for infants, the risk was reduced if the mother had had multiple previous pregnancies (OR = 0.39, 95% CI: 0.22, 0.69). These data suggest that etiologic factors associated with the prenatal and perinatal periods may be specific to age at neuroblastoma diagnosis.

Birth characteristics and risk of neuroblastoma in young children. Publishing Authors By Initials

KY Urayama,J Von Behren,P Reynolds,

For similar investigative techniques: epidemiologic methods: statistics as topic: probability: risk: risk factors research abstracts see: investigative techniques: epidemiologic methods: statistics as topic: probability: risk: risk factors research

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Birth characteristics and risk of neuroblastoma in young children. Journal Published:

PUBLICATION TYPE: Research Support, N.I.H., Extr

Journal: American journal of epidemiology

VOLUME: 165

Page Numbers: 486-95

Journal Abbreviation: Am. J. Epidemiol.

ISSN: 0002-9262

DAY: 12

MONTH: 12

YEAR: 2006

Birth characteristics and risk of neuroblastoma in young children. Information

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LANGUAGE: eng

NlmUniqueID: 7910653

Birth characteristics and risk of neuroblastoma in young children. Keywords Mesh Terms:

KEYWORDS: Risk Factors

MESH TERMS: ethnology

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Grant and Affiliation Information for Birth characteristics and risk of neuroblastoma in young children.

AFFILIATION: Division of Epidemiology, School of Public Health, University of California, Berkeley, CA, USA.

Country: United States

AGENCY: United States NCI

GRANT: R01 CA71745

ACRONYM: CA

MEDLINETA: Am J Epidemiol

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