[Biotherapy of Cancer by Anti-EGFR Monoclonal Antibody - Review.]

[Biotherapy of Cancer by Anti-EGFR Monoclonal Antibody - Review.] Research Abstract Details 

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[Biotherapy of Cancer by Anti-EGFR Monoclonal Antibody - Review.] Abstract Text:

Jing Wang,Zhi-Yun Meng,Sou-Ting Fu,Gui-Fang Dou,Jing Wang,Zhi-Yun Meng,Sou-Ting Fu,Gui-Fang Dou,

Epidermal growth factor receptor (EGFR) is mutated, dysregulated or overexpressed in many epithelial malignancies, and EGFR activation has been found to be important in tumor growth and progression. Anti-EGFR monoclonal antibodies target the extracellular domain of EGFR; and show promising anti-tumor potential at clinical trials without severe side effects. In this article the pharmacokenetics and clinical study of 3 anti-EGFR monoclonal antibodies (cetuximab, panitumumab and nimotuzomab) were reviewed.

[Biotherapy of Cancer by Anti-EGFR Monoclonal Antibody - Review.] Publishing Authors By Initials

J Wang,ZY Meng,ST Fu,GF Dou,J Wang,ZY Meng,ST Fu,GF Dou,

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[Biotherapy of Cancer by Anti-EGFR Monoclonal Antibody - Review.] Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Zhongguo shi yan xue ye xue za zhi / Zhongguo bing

VOLUME: 15

Page Numbers: 1135-8

Journal Abbreviation: Zhongguo Shi Yan Xue Ye Xue Za

ISSN: 1009-2137

DAY: 24

MONTH: Oct

YEAR: 2007

[Biotherapy of Cancer by Anti-EGFR Monoclonal Antibody - Review.] Information

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LANGUAGE: chi

NlmUniqueID: 101084424

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AFFILIATION: Key Laboratory of Pharmacokinetics, Institute of Transfusion Medicine, Academy of Military Medical Sciences, Beijing 100850, China; Department of Pharmacology, School of Pharmacy, Shenyang Pharmaceutical University, Shenyang 110016, China.

Country: China

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MEDLINETA: Zhongguo Shi Yan Xue Ye Xue Za

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