Biomimetic coating of an apatite layer on poly(L-lactic acid); improvement of adhesive strength of the coating.

Biomimetic coating of an apatite layer on poly(L-lactic acid); improvement of adhesive strength of the coating. Research Abstract Details 

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Biomimetic coating of an apatite layer on poly(L-lactic acid); improvement of adhesive strength of the coating. Abstract Text:

Yoshiro Yokoyama,Ayako Oyane,Atsuo Ito,

A biodegradable polymer coated with a bonelike apatite layer on its surface would be useful as a scaffold for bone tissue regeneration. In this study, poly(L-lactic acid) (PLLA) was treated with oxygen plasma to produce oxygen-containing functional groups on its surface. The plasma-treated specimen was then alternately dipped in aqueous CaCl(2) and K(2)HPO(4).3H(2)O solutions three times, to deposit apatite precursors onto the surface. The surface-modified specimen then successfully formed a dense and uniform bonelike surface apatite layer after immersion for 24 h in a simulated body fluid with ion concentrations approximately equal to those of human blood plasma. The adhesive strength between the apatite layer and the specimen surface increased as the power density of the oxygen plasma used increased. The maximum adhesive strength of the apatite layer to the specimen was significantly higher than that to the commercially available artificial bone, HAPEX. The resultant bonelike apatite-PLLA composite would be useful as a scaffold for bone tissue regeneration.

Biomimetic coating of an apatite layer on poly(L-lactic acid); improvement of adhesive strength of the coating. Publishing Authors By Initials

Y Yokoyama,A Oyane,A Ito,

For similar natural sciences: physics: radiation: radiation, ionizing: x-rays research abstracts see: natural sciences: physics: radiation: radiation, ionizing: x-rays research

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Biomimetic coating of an apatite layer on poly(L-lactic acid); improvement of adhesive strength of the coating. Journal Published:

PUBLICATION TYPE: Research Support, Non-U.S. Gov

Journal: Journal of materials science. Materials in medicin

VOLUME: 18

Page Numbers: 1727-34

Journal Abbreviation:

ISSN: 0957-4530

DAY: 5

MONTH: 05

YEAR: 2007

Biomimetic coating of an apatite layer on poly(L-lactic acid); improvement of adhesive strength of the coating. Information

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LANGUAGE: eng

NlmUniqueID: 9013087

Biomimetic coating of an apatite layer on poly(L-lactic acid); improvement of adhesive strength of the coating. Keywords Mesh Terms:

KEYWORDS: X-Rays

MESH TERMS: chemistry

Chemical & Substance for Abstract: Biomimetic coating of an apatite layer on poly(L-lactic acid); improvement of adhesive strength of the coating. Information

Substance Name: Lactic Acid

Registry Number: 50-21-5

Grant and Affiliation Information for Biomimetic coating of an apatite layer on poly(L-lactic acid); improvement of adhesive strength of the coating.

AFFILIATION: Nanotechnology Research Institute, National Institute of Advanced Industrial Science and Technology (AIST), Central 4, 1-1-1, Higashi, Tsukuba-Shi, Ibaraki, Japan.

Country: United States

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MEDLINETA: J Mater Sci Mater Med

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