Biometric measurements of the eyes in teenagers and young adults with Down syndrome.

Biometric measurements of the eyes in teenagers and young adults with Down syndrome. Research Abstract Details 

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Biometric measurements of the eyes in teenagers and young adults with Down syndrome. Abstract Text:

PURPOSE: To examine ocular biometric variables in subjects with Down syndrome. METHODS: In a population-based study we have compared ocular biometric variables in a group of 47 individuals with Down syndrome (20.0+/-3.9 years) with 51 control subjects (21.0+/-4.6 years). RESULTS: A thinner cornea (0.48+/-0.04 mm vs. 0.55+/-0.03 mm, p<0.001) and higher keratometry values (46.39+/-1.95 D vs. 43.41+/-1.40 D, p<0.001) were found in the Down syndrome group than in the control group. Oblique astigmatism was commonly found in the Down syndrome individuals, showing a strong right-left specificity (right eyes' axes in the 135 degrees -meridian, left eyes' axes in the 45 degrees -meridian). The lens was thinner (3.27+/-0.29 mm vs. 3.49+/-0.20 mm) and the calculated lens power was weaker (17.70+/-2.36 D vs. 19.48+/-1.24 D) in the Down syndrome group than in the control group (p<0.001 in both cases). CONCLUSIONS: Thinning of the corneal stroma may account for the steeper cornea and the high frequency of astigmatism in Down syndrome due to lower corneal rigidity. It may also be of etiological importance to the increased incidence of keratoconus in Down syndrome.

Biometric measurements of the eyes in teenagers and young adults with Down syndrome. Publishing Authors By Initials

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Biometric measurements of the eyes in teenagers and young adults with Down syndrome. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Acta ophthalmologica Scandinavica

VOLUME: 79

Page Numbers: 616-25

Journal Abbreviation: Acta Ophthalmol Scand

ISSN: 1395-3907

DAY: 17

MONTH: Dec

YEAR: 2001

Biometric measurements of the eyes in teenagers and young adults with Down syndrome. Information

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LANGUAGE: eng

NlmUniqueID: 9507578

Biometric measurements of the eyes in teenagers and young adults with Down syndrome. Keywords Mesh Terms:

KEYWORDS: Visual Acuity

MESH TERMS: methods

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Grant and Affiliation Information for Biometric measurements of the eyes in teenagers and young adults with Down syndrome.

AFFILIATION: Department of Ophthalmology, Haukeland University Hospital, N-5021 Bergen, Norway. olav.haugen@haukeland.no

Country: Denmark

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MEDLINETA: Acta Ophthalmol Scand

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