Biomathematics in cancer detection: simulation of lipogenesis in cancer.

Biomathematics in cancer detection: simulation of lipogenesis in cancer. Research Abstract Details 

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Biomathematics in cancer detection: simulation of lipogenesis in cancer. Abstract Text:

Ping Huang,Britton Chance,Ping Huang,Britton Chance,

The usual mechanisms for biochemical events are steady-state systems without dynamic simulation. Our study is to simulate lipogenesis from the breakdown of glucose coupled with oxidative phosphorylation in mitochondria by using JSim (for Java Simulator) as software development environment, which enables non-linear differential equations to be used in a simulation giving a time course through a variety of non-steady-state conditions. Glycolysis and lipogenesis coupled with oxidative phosphorylation in mitochondria non-linear differential model is built in this paper. Simulation and discussion on lipogenesis by carbohydrate responsive element-binding protein (ChREBP) are given. Our model provides a potential way to analyze the experimental databank.

Biomathematics in cancer detection: simulation of lipogenesis in cancer. Publishing Authors By Initials

P Huang,B Chance,P Huang,B Chance,

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Biomathematics in cancer detection: simulation of lipogenesis in cancer. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Advances in experimental medicine and biology

VOLUME: 614

Page Numbers: 151-6

Journal Abbreviation: Adv. Exp. Med. Biol.

ISSN: 0065-2598

DAY: 22

MONTH: 02

YEAR: 2008

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LANGUAGE: eng

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AFFILIATION: Department of Biophysics and Biochemistry, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA. huangping2001@hotmail.com

Country: United States

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MEDLINETA: Adv Exp Med Biol

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