Biomarker discovery in human SLE nephritis.

Biomarker discovery in human SLE nephritis. Research Abstract Details

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Biomarker discovery in human SLE nephritis. Abstract Text:

Brad H Rovin,Daniel J Birmingham,Haikady N Nagaraja,C Yung Yu,Lee A Hebert,Brad H Rovin,Daniel J Birmingham,Haikady N Nagaraja,C Yung Yu,Lee A Hebert,Brad H Rovin,Daniel J Birmingham,Haikady N Nagaraja,C Yung Yu,Lee A Hebert,

The treatment of systemic lupus erythematosus (SLE) nephritis, while effective, is associated with significant morbidity and mortality. These side effects could be mitigated if the onset, severity, and response of renal flare could be predicted, and therapy modified accordingly. In this review, an approach to derive prediction equations of SLE nephritis flare is discussed. Integral to generating such prediction equations is the identification of biomarkers of lupus nephritis that can serve as input variables for modeling flare. The use of urine as a source of SLE nephritis biomarkers is described, and the results of urine biomarker discovery studies using candidate and proteomic approaches are presented.

Biomarker discovery in human SLE nephritis. Publishing Authors By Initials

BH Rovin,DJ Birmingham,HN Nagaraja,CY Yu,LA Hebert,BH Rovin,DJ Birmingham,HN Nagaraja,CY Yu,LA Hebert,BH Rovin,DJ Birmingham,HN Nagaraja,CY Yu,LA Hebert,

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Biomarker discovery in human SLE nephritis. Journal Published:

PUBLICATION TYPE: Research Support, N.I.H., Extr

Journal: Bulletin of the NYU hospital for joint diseases

VOLUME: 65

Page Numbers: 187-93

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ISSN: 1936-9719

DAY: 9

MONTH: 10

YEAR: 2007

Biomarker discovery in human SLE nephritis. Information

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LANGUAGE: eng

NlmUniqueID: 101300541

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AFFILIATION: Division of Nephrology, Ohio State University College of Medicine, and Columbus Children's Hospital Research Center 43210, USA. Rovin.1@osu.edu

Country: United States