Biology-inspired synthesis of compound libraries.

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Biology-inspired synthesis of compound libraries. Abstract Text:

Biologically active small molecules represent the basis for chemical biology applications in which small molecules are used as chemical tools to probe biological processes. In this report, we review two approaches to design and synthesize compound libraries for biological screenings, i.e., diversity-oriented synthesis (DOS) and biology-oriented synthesis (BIOS).

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PUBLICATION TYPE: Journal Article

Journal: Cellular and molecular life sciences : CMLS

VOLUME: 65

Page Numbers: 1186-201

Journal Abbreviation: Cell. Mol. Life Sci.

ISSN: 1420-682X

DAY: 21

MONTH: Apr

YEAR: 2008

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LANGUAGE: eng

NlmUniqueID: 9705402

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Grant and Affiliation Information for Biology-inspired synthesis of compound libraries.

AFFILIATION: Chemical Genomics Centre of the Max Planck Society, Otto-Hahn-Str. 15, Dortmund, 44227, Germany.

Country: Switzerland

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MEDLINETA: Cell Mol Life Sci

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