Tumor Markers, Biological

- 18F-FDG PET scanning correlates with tissue markers of poor prognosis and predicts mortality for patients after liver resection for colorectal metastases. (18)F-FDG PET has proven invaluable in the staging of patients with metastatic colorectal cancer. The aim of the current study was to determine whether this...

- 18q loss of heterozygosity in microsatellite stable colorectal cancer is correlated with CpG island methylator phenotype-negative (CIMP-0) and inversely with CIMP-low and CIMP-high. BACKGROUND: The CpG island methylator phenotype (CIMP) with widespread promoter methylation is a distinct epigenetic phenotype in colorectal cancer,...

- A 33-year-old man with multiple ring-enhancing lesions in the brain.

- A case of spontaneous regression of metastatic testicular teratoma. We report the apparently spontaneous regression of metastatic disease in a young man who had previously undergone orchidectomy for a primary testicular...

- A disposable two-throughput electrochemical immunosensor chip for simultaneous multianalyte determination of tumor markers. A disposable two-throughput immunosensor array was proposed for simultaneous electrochemical determination of tumor markers. The low-cost immunosensor array...

- A large noncoding RNA is a marker for murine hepatocellular carcinomas and a spectrum of human carcinomas. Tumor markers can facilitate understanding molecular cell biology of neoplasia and provide potential targets for the diagnosis and insight for intervention....

- A marker and putative pathoantigen of Hodgkin's cells. A galactose-specific lectin, recently described by our laboratory, is immunologically demonstrable on the surface of neoplastic cells derived from patients...

- A meta-analysis of reverse transcriptase-polymerase chain reaction for tyrosinase mRNA as a marker for circulating tumor cells in cutaneous melanoma. OBJECTIVE: To systematically review the use of reverse transcriptase-polymerase chain reaction (RT-PCR) for tyrosinase messenger RNA as a molecular serum...

- A multigenic approach to predict breast cancer risk. In the biology of complex disorders, such as breast cancer, interactions among genetic factors may play an important role and theoretical considerations...

- A new hypothesis on the cellular origin of Reed-Sternberg and Hodgkin cells based on the immunological and molecular genetic analysis of the KM-H2 line.

- A noninvasive multimodal technique to monitor brain tumor vascularization. Determination of tumor oxygenation at the microvascular level will provide important insight into tumor growth, angiogenesis, necrosis and therapeutic...

- A novel family of slitrk genes is expressed on hematopoietic stem cells and leukemias.

- A novel gastric-cancer-associated mucin antigen defined by a monoclonal antibody A3D4. De-glycosylation of mucins may expose new tumor-associated core protein epitopes. In this study, to attempt to develop useful markers for gastric cancers, we...

- A peptide selected by biopanning identifies the integrin alphavbeta6 as a prognostic biomarker for nonsmall cell lung cancer. The development of new modes of diagnosis and targeted therapy for lung cancer is dependent on the identification of unique cell surface features on cancer...

- A prospective study of plasma prolactin concentrations and risk of premenopausal and postmenopausal breast cancer. PURPOSE: Epidemiologic studies suggest that prolactin is associated with breast cancer risk in older women. Because of limited prospective data, particularly...

- A randomized trial of lycopene supplementation in Tobago men with high prostate cancer risk. This unblinded, randomized, Phase I clinical trial was conducted to determine whether lycopene supplementation lowered serum prostate specific antigen (PSA),...

- A rational approach to the follow-up of melanoma patients. There are no generally accepted guidelines for the follow-up of cutaneous melanoma (CM), and there is an ongoing debate about the value of follow-up...

- A renal hemangiosarcoma causing hematuria in a dog. A 14.5-year-old male dog was presented with stranguria and hematuria of 1-month duration. Hematology and blood chemistry revealed a neutrophilia, mild...

- A serum glycomics approach to breast cancer biomarkers. Because the glycosylation of proteins is known to change in tumor cells during the development of breast cancer, a glycomics approach is used here to find...

- A strong association between body fat mass and protein profiles in nipple aspirate fluid of healthy premenopausal non-lactating women. Fluid can be aspirated from the nipples of most non-lactating women. This nipple aspirate fluid (NAF) is a potential source for the discovery of new breast...