Biodegradation and biocompatability of a calcium sulphate-hydroxyapatite bone substitute.

Biodegradation and biocompatability of a calcium sulphate-hydroxyapatite bone substitute. Research Abstract Details 

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Biodegradation and biocompatability of a calcium sulphate-hydroxyapatite bone substitute. Abstract Text:

M Nilsson,J S Wang,L Wielanek,K E Tanner,L Lidgren,

An injectable material consisting of calcium sulphate mixed with hydroxyapatite was investigated as a possible alternative to autograft in the restoration of bone defects. The material was studied both in vitro in simulated body fluid (SBF) and in vivo when implanted in rat muscles and into the proximal tibiae of rabbits. Variation in the strength and weight of the material during ageing in SBF was measured. Tissue response, material resorption and bone ingrowth were studied in the animal models. A good tissue response was observed in both the rat muscles and rabbit tibiae without inflammatory reactions or the presence of fibrous tissue. Ageing in SBF showed that during the first week carbonated hydroxyapatite precipitated on the surfaces of the material and this may enhance bone ingrowth.

Biodegradation and biocompatability of a calcium sulphate-hydroxyapatite bone substitute. Publishing Authors By Initials

M Nilsson,JS Wang,L Wielanek,KE Tanner,L Lidgren,

For similar musculoskeletal system: skeleton: bone and bones: bones of lower extremity: leg bones: tibia research abstracts see: musculoskeletal system: skeleton: bone and bones: bones of lower extremity: leg bones: tibia research

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Biodegradation and biocompatability of a calcium sulphate-hydroxyapatite bone substitute. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: The Journal of bone and joint surgery. British vol

VOLUME: 86

Page Numbers: 120-5

Journal Abbreviation:

ISSN: 0301-620X

DAY: 14

MONTH: Jan

YEAR: 2004

Biodegradation and biocompatability of a calcium sulphate-hydroxyapatite bone substitute. Information

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LANGUAGE: eng

NlmUniqueID: 375355

Biodegradation and biocompatability of a calcium sulphate-hydroxyapatite bone substitute. Keywords Mesh Terms:

KEYWORDS: Tibia

MESH TERMS: metabolism

Chemical & Substance for Abstract: Biodegradation and biocompatability of a calcium sulphate-hydroxyapatite bone substitute. Information

Substance Name: Calcium Sulfate

Registry Number: 7778-18-9

Grant and Affiliation Information for Biodegradation and biocompatability of a calcium sulphate-hydroxyapatite bone substitute.

AFFILIATION: Biomaterials and Biomechanics Lab, C12-BMC, Department of Orthopaedics, Lund University Hospital, S-221 85 Lund, Sweden.

Country: England

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MEDLINETA: J Bone Joint Surg Br

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