Biochemical verification of smoking status in pregnant and recently postpartum women.

Biochemical verification of smoking status in pregnant and recently postpartum women. Research Abstract Details 

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Biochemical verification of smoking status in pregnant and recently postpartum women. Abstract Text:

Stephen T Higgins,Sarah H Heil,Gary J Badger,Joan A Mongeon,Laura J Solomon,Luke McHale,Ira M Bernstein,

The present study was conducted to examine several different methods and cutpoints for determining smoking status in pregnant and recently postpartum women. Self-reported smoking status, urine cotinine levels determined by gas chromatography (GC) and by enzyme immunoassay testing (EMIT), and breath carbon monoxide (CO) levels were assessed at 28 weeks antepartum and 12 and 24 weeks postpartum in 131 women enrolled in studies on smoking cessation and relapse prevention. Classifications based on urine-cotinine GC testing served as the standard in most analyses. Overall agreement between self-reported smoking status and classification based on urine-cotinine GC testing was excellent (> or =95%) at several cutpoints (50, 25, and 12.5 ng/ml) but highest at 25 ng/ml. Classifications based on EMIT urine cotinine levels were in nearly perfect (> or =98%) agreement with those made by GC when the cutpoint for the former was set at approximately 80 ng/ml (79-87 ng/ml). Classifications based on breath CO were in relatively poor agreement (< or =87%) with GC classifications at all cutpoints examined but best at 4 ppm. Overall, these results provide detailed information on several commonly used methods for classifying smoking in pregnant and recently postpartum women that should be practically useful to researchers and clinicians involved in efforts to eliminate smoking in this population.

Biochemical verification of smoking status in pregnant and recently postpartum women. Publishing Authors By Initials

ST Higgins,SH Heil,GJ Badger,JA Mongeon,LJ Solomon,L McHale,IM Bernstein,

For similar geographic locations: americas: north america: united states: new england: vermont research abstracts see: geographic locations: americas: north america: united states: new england: vermont research

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MEDLINE DATE:

Biochemical verification of smoking status in pregnant and recently postpartum women. Journal Published:

PUBLICATION TYPE: Research Support, N.I.H., Extr

Journal: Experimental and clinical psychopharmacology

VOLUME: 15

Page Numbers: 58-66

Journal Abbreviation:

ISSN: 1064-1297

DAY: 3

MONTH: Feb

YEAR: 2007

Biochemical verification of smoking status in pregnant and recently postpartum women. Information

Number of References:

LANGUAGE: eng

NlmUniqueID: 9419066

Biochemical verification of smoking status in pregnant and recently postpartum women. Keywords Mesh Terms:

KEYWORDS: Vermont

MESH TERMS: urine

Chemical & Substance for Abstract: Biochemical verification of smoking status in pregnant and recently postpartum women. Information

Substance Name: Carbon Monoxide

Registry Number: 630-08-0

Grant and Affiliation Information for Biochemical verification of smoking status in pregnant and recently postpartum women.

AFFILIATION: Department of Psychiatry, University of Vermont, Burlington, VT 05401, USA. stephen.higgins@uvm.edu

Country: United States

AGENCY: United States NIDA

GRANT: R01DA14028

ACRONYM: DA

MEDLINETA: Exp Clin Psychopharmacol

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