Bioactive constituents from Chinese natural medicines. XXVI. Chemical structures and hepatoprotective effects of constituents from roots of Rhodiola sachalinensis.

Bioactive constituents from Chinese natural medicines. XXVI. Chemical structures and hepatoprotective effects of constituents from roots of Rhodiola sachalinensis. Research Abstract Details 

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Bioactive constituents from Chinese natural medicines. XXVI. Chemical structures and hepatoprotective effects of constituents from roots of Rhodiola sachalinensis. Abstract Text:

Seikou Nakamura,Xuezheng Li,Hisashi Matsuda,Kiyofumi Ninomiya,Toshio Morikawa,Kikuji Yamaguti,Masayuki Yoshikawa,Seikou Nakamura,Xuezheng Li,Hisashi Matsuda,Kiyofumi Ninomiya,Toshio Morikawa,Kikuji Yamaguti,Masayuki Yoshikawa,

The methanolic extract from the roots of Rhodiola sachalinensis was found to show a protective effect on D-galactosamine-induced cytotoxicity in primary cultured mouse hepatocytes. From the methanolic extract, five new glycosides, two monoterpene glycosides, two flavonol bisdesmosides, and a cyanogenic glycoside, were isolated together with 34 known compounds. The structures of new constituents were elucidated on the basis of chemical and physicochemical evidence. In addition, the principal constituents, sachalosides III and IV, rhodiosin, and trans-caffeic acid, displayed hepatoprotective effects.

Bioactive constituents from Chinese natural medicines. XXVI. Chemical structures and hepatoprotective effects of constituents from roots of Rhodiola sachalinensis. Publishing Authors By Initials

S Nakamura,X Li,H Matsuda,K Ninomiya,T Morikawa,K Yamaguti,M Yoshikawa,S Nakamura,X Li,H Matsuda,K Ninomiya,T Morikawa,K Yamaguti,M Yoshikawa,

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Bioactive constituents from Chinese natural medicines. XXVI. Chemical structures and hepatoprotective effects of constituents from roots of Rhodiola sachalinensis. Journal Published:

PUBLICATION TYPE: Research Support, Non-U.S. Gov

Journal: Chemical & pharmaceutical bulletin

VOLUME: 55

Page Numbers: 1505-11

Journal Abbreviation: Chem. Pharm. Bull.

ISSN: 0009-2363

DAY: 5

MONTH: Oct

YEAR: 2007

Bioactive constituents from Chinese natural medicines. XXVI. Chemical structures and hepatoprotective effects of constituents from roots of Rhodiola sachalinensis. Information

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LANGUAGE: eng

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Grant and Affiliation Information for Bioactive constituents from Chinese natural medicines. XXVI. Chemical structures and hepatoprotective effects of constituents from roots of Rhodiola sachalinensis.

AFFILIATION: Kyoto Pharmaceutical University, Kyoto, Japan.

Country: Japan

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MEDLINETA: Chem Pharm Bull (Tokyo)

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