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Binding of 99mTc(113Sn)-MDP to human serum albumin. The influence of various technetium, tin, and MDP concentrations.

Binding of 99mTc(113Sn)-MDP to human serum albumin. The influence of various technetium, tin, and MDP concentrations. Research Abstract Details 

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  • Binding of 99mTc(113Sn)-MDP to human serum albumin. The influence of various technetium, tin, and MDP concentrations. Abstract Text:

    r j groulsR J Grouls,s j oldenburgS J Oldenburg,t j savelkoulT J Savelkoul,j h drögeJ H Dröge,

    The HSA-binding of 99mTc incubated as 99mTc(113Sn)-MDP depends in vitro on the presence of competing anions normally present in plasma and on the MDP and Tc concentration, but is independent of the Sn concentration. The HSA-binding of 113Sn depends on the MDP and Sn concentration; not on the Tc concentration. 99mTc(Sn)-MDP binds to HSA as a unit. The binding of 99mTc(Sn)-MDP to plasma proteins in vivo is much lower as calculated from in vitro experiments because of competition between 99mTc(Sn)-MDP and endogenous anions for the same binding-sites.

    Binding of 99mTc(113Sn)-MDP to human serum albumin. The influence of various technetium, tin, and MDP concentrations. Publishing Authors By Initials

    rj groulsRJ Grouls,sj oldenburgSJ Oldenburg,tj savelkoulTJ Savelkoul,jh drögeJH Dröge,

    For similar inorganic chemicals: elements: metals, heavy: tin research abstracts see: inorganic chemicals: elements: metals, heavy: tin research

    PUBMED ID PMID:

    MEDLINE DATE:

    Binding of 99mTc(113Sn)-MDP to human serum albumin. The influence of various technetium, tin, and MDP concentrations. Journal Published:

    PUBLICATION TYPE: Journal Article

    Journal: International journal of radiation applications an

    VOLUME: 14

    Page Numbers: 127-32

    Journal Abbreviation:

    ISSN: 0883-2897

    DAY: 21

    MONTH: 02

    YEAR: 1987

    Binding of 99mTc(113Sn)-MDP to human serum albumin. The influence of various technetium, tin, and MDP concentrations. Information

    Number of References:

    LANGUAGE: eng

    NlmUniqueID: 8611098

    Binding of 99mTc(113Sn)-MDP to human serum albumin. The influence of various technetium, tin, and MDP concentrations. Keywords Mesh Terms:

    KEYWORDS: Tin

    MESH TERMS: pharmacology

    Chemical & Substance for Abstract: Binding of 99mTc(113Sn)-MDP to human serum albumin. The influence of various technetium, tin, and MDP concentrations. Information

    Substance Name: Tin

    Registry Number: 7440-31-5

    Grant and Affiliation Information for Binding of 99mTc(113Sn)-MDP to human serum albumin. The influence of various technetium, tin, and MDP concentrations.

    AFFILIATION:

    Country: UNITED STATES

    UNITED STATES Research PublicationUNITED STATES Research Publication

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    GRANT:

    ACRONYM:

    MEDLINETA: Int J Rad Appl Instrum B

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    Binding of 99mTc113Sn-MDP to human serum albumin The influence of various technetium, tin, and MDP concentrations Related Publications

     

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