Bilateral diffuse uveal melanocytic proliferation and uterine cancer. A case report.

Bilateral diffuse uveal melanocytic proliferation and uterine cancer. A case report. Research Abstract Details 

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Bilateral diffuse uveal melanocytic proliferation and uterine cancer. A case report. Abstract Text:

PURPOSE: To report a case of bilateral diffuse uveal melanocytic proliferation (BDUMP), a rare paraneoplastic syndrome causing visual loss in patients with systemic carcinoma. RESULTS: A 70-year-old woman developed visual symptoms 13 months after surgery and local irradiation therapy for uterine cancer. Following bilateral external beam irradiation supplemented with subsequent drainage of subretinal fluid in the left eye, the visual acuity improved from 0.01 to 0.15 in this eye only. The visual acuity remained at this level until she died 4 1/4 years after the onset of eye symptoms. CONCLUSION: This is the fourth case that survived longer than 24 months after the onset of visual symptoms of the 22 previously reported cases with BDUMP. It demonstrates that radiotherapy may have a vision-preserving effect in this group of patients. The patient also developed two different paraneoplastic phenomena--a nephrotic syndrome before and BDUMP after treatment for uterine cancer.

Bilateral diffuse uveal melanocytic proliferation and uterine cancer. A case report. Publishing Authors By Initials

For similar eye diseases: uveal diseases research abstracts see: eye diseases: uveal diseases research

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Bilateral diffuse uveal melanocytic proliferation and uterine cancer. A case report. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Acta ophthalmologica Scandinavica

VOLUME: 78

Page Numbers: 366-8

Journal Abbreviation: Acta Ophthalmol Scand

ISSN: 1395-3907

DAY: 17

MONTH: Jun

YEAR: 2000

Bilateral diffuse uveal melanocytic proliferation and uterine cancer. A case report. Information

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LANGUAGE: eng

NlmUniqueID: 9507578

Bilateral diffuse uveal melanocytic proliferation and uterine cancer. A case report. Keywords Mesh Terms:

KEYWORDS: Uveal Diseases

MESH TERMS: therapy

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Grant and Affiliation Information for Bilateral diffuse uveal melanocytic proliferation and uterine cancer. A case report.

AFFILIATION: University Eye Department, The National Hospital, University of Oslo, Norway.

Country: DENMARK

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MEDLINETA: Acta Ophthalmol Scand

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