Beta-galactosidase-neuraminidase deficiency: restoration of beta-galactosidase activity by protease inhibitors.

Beta-galactosidase-neuraminidase deficiency: restoration of beta-galactosidase activity by protease inhibitors. Research Abstract Details 

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Beta-galactosidase-neuraminidase deficiency: restoration of beta-galactosidase activity by protease inhibitors. Abstract Text:

Y Suzuki,H Sakuraba,K Hayashi,K Suzuki,K Imahori,

Beta-Galactosidase was partially restored by protease inhibitors, leupeptin, chymostatin and E-64 in cultured fibroblasts from three patients with beta-galactosidase-neuraminidase deficiency. Pepstatin did not activate this enzyme. Neuraminidase was not affected by any of these compounds in the culture medium. It was concluded that the activating effect was produced by a specific inhibition of thiol proteases.

Beta-galactosidase-neuraminidase deficiency: restoration of beta-galactosidase activity by protease inhibitors. Publishing Authors By Initials

Y Suzuki,H Sakuraba,K Hayashi,K Suzuki,K Imahori,

For similar enzymes and coenzymes: enzymes: hydrolases: glycoside hydrolases: galactosidases: beta-galactosidase research abstracts see: enzymes and coenzymes: enzymes: hydrolases: glycoside hydrolases: galactosidases: beta-galactosidase research

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Beta-galactosidase-neuraminidase deficiency: restoration of beta-galactosidase activity by protease inhibitors. Journal Published:

PUBLICATION TYPE: Research Support, Non-U.S. Gov

Journal: Journal of biochemistry

VOLUME: 90

Page Numbers: 271-3

Journal Abbreviation: J. Biochem.

ISSN: 0021-924X

DAY: 19

MONTH: Jul

YEAR: 1981

Beta-galactosidase-neuraminidase deficiency: restoration of beta-galactosidase activity by protease inhibitors. Information

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LANGUAGE: eng

NlmUniqueID: 376600

Beta-galactosidase-neuraminidase deficiency: restoration of beta-galactosidase activity by protease inhibitors. Keywords Mesh Terms:

KEYWORDS: beta-Galactosidase

MESH TERMS: metabolism

Chemical & Substance for Abstract: Beta-galactosidase-neuraminidase deficiency: restoration of beta-galactosidase activity by protease inhibitors. Information

Substance Name: beta-Galactosidase

Registry Number: EC 3.2.1.23

Grant and Affiliation Information for Beta-galactosidase-neuraminidase deficiency: restoration of beta-galactosidase activity by protease inhibitors.

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Country: JAPAN

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MEDLINETA: J Biochem

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