Microinjections of beta-alanine and glycine into the nucleus tractus solitarii (NTS) of the rat, led to an increase in blood pressure and heart rate. The responses to glycine but not to beta-alanine could be blocked by strychnine. Both amino acids reduced the responses to aortic nerve stimulation. High K+ stimulation caused a calcium-dependent release of beta-alanine from tissues in the area of the NTS. These results suggest that beta-alanine and glycine may modulate the cardiovascular control within the NTS.
Beta-alanine, like glycine, microinjected into the rat nucleus tractus solitarii increases blood pressure. Publishing Authors By Initials
Beta-alanine, like glycine, microinjected into the rat nucleus tractus solitarii increases blood pressure. Journal Published:
PUBLICATION TYPE: Research Support, Non-U.S. Gov
Journal: Clinical and experimental hypertension. Part A, Th
VOLUME: 12
Page Numbers: 1351-60
Journal Abbreviation:
ISSN: 0730-0077
DAY: 12
MONTH: 02
YEAR: 1990
Beta-alanine, like glycine, microinjected into the rat nucleus tractus solitarii increases blood pressure. Information
Number of References:
LANGUAGE: eng
NlmUniqueID: 8207790
Beta-alanine, like glycine, microinjected into the rat nucleus tractus solitarii increases blood pressure. Keywords Mesh Terms:
KEYWORDS: beta-Alanine
MESH TERMS: administration & dosage
Chemical & Substance for Abstract: Beta-alanine, like glycine, microinjected into the rat nucleus tractus solitarii increases blood pressure. Information
Substance Name: Calcium
Registry Number: 7440-70-2
Grant and Affiliation Information for Beta-alanine, like glycine, microinjected into the rat nucleus tractus solitarii increases blood pressure.
AFFILIATION: Department of Pharmacology, Yokohama City University, School of Medicine, Japan.
Country: UNITED STATES
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GRANT:
ACRONYM:
MEDLINETA: Clin Exp Hypertens A
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