Basis and consequences of primary and secondary prevention of gastrointestinal tumors.

Basis and consequences of primary and secondary prevention of gastrointestinal tumors. Research Abstract Details 

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Basis and consequences of primary and secondary prevention of gastrointestinal tumors. Abstract Text:

P Goldin-Lang,E D Kreuser,H J Zunft,

Carcinomas of the gastrointestinal tract (GI) are among the most common malignancies with regard to their incidence and mortality. Nutritional factors play an important role in the tumor development. The strength of their influence varies with the localization in the GI tract. Epidemiological studies focusing on GI cancer incidence or mortality as an endpoint necessitate large numbers of subjects to achieve significant results. Generally, a low energy and fat intake and a high intake of antioxidative vitamins (vitamin C, E, beta-carotene) and secondary plant metabolites (especially polyphenols) appear to be protective in GI carcinogenesis. Moderate drinking of alcohol and increased consumption of whole grain products, as opposed to highly refined carbohydrates, may help to reduce the risk of colon cancer. The recommended type of diet is low in fat, especially in saturated fatty acids, includes monounsaturated fatty acids, and includes moderate amounts of polyunsaturated fatty acids (no more than 10% of calories). Moderate consumption of salt and of highly salted, smoked, and barbecued foods should be encouraged. Obesity should be avoided by trying to match energy intake with expenditure while increasing physical activity levels. The mechanisms by which nutritional factors act especially on molecular events still remain to be examined. The use of molecular biomarkers will help us better understand cancer development as well as the role and significance of nutritional factors in this process.

Basis and consequences of primary and secondary prevention of gastrointestinal tumors. Publishing Authors By Initials

P Goldin-Lang,ED Kreuser,HJ Zunft,

For similar digestive system: gastrointestinal tract: intestines research abstracts see: digestive system: gastrointestinal tract: intestines research

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Basis and consequences of primary and secondary prevention of gastrointestinal tumors. Journal Published:

PUBLICATION TYPE: Review

Journal: Recent results in cancer research. Fortschritte de

VOLUME: 142

Page Numbers: 163-92

Journal Abbreviation: Recent Results Cancer Res.

ISSN: 0080-0015

DAY: 13

MONTH: 02

YEAR: 1996

Basis and consequences of primary and secondary prevention of gastrointestinal tumors. Information

Number of References: 127

LANGUAGE: eng

NlmUniqueID: 44671

Basis and consequences of primary and secondary prevention of gastrointestinal tumors. Keywords Mesh Terms:

KEYWORDS: Intestines

MESH TERMS: microbiology

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Grant and Affiliation Information for Basis and consequences of primary and secondary prevention of gastrointestinal tumors.

AFFILIATION: Department of Epidemiology and Nutritional Behavior, German Institute of Human Nutrition, Bergholz-Rehbruecke, Germany.

Country: GERMANY

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MEDLINETA: Recent Results Cancer Res

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