Barriers to clinical trial participation as perceived by oncologists and patients.

Barriers to clinical trial participation as perceived by oncologists and patients. Research Abstract Details 

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Barriers to clinical trial participation as perceived by oncologists and patients. Abstract Text:

Neal J Meropol,Joanne S Buzaglo,Jennifer Millard,Nevena Damjanov,Suzanne M Miller,Caroline Ridgway,Eric A Ross,John D Sprandio,Perry Watts,Neal J Meropol,Joanne S Buzaglo,Jennifer Millard,Nevena Damjanov,Suzanne M Miller,Caroline Ridgway,Eric A Ross,John D Sprandio,Perry Watts,

Although clinical trial research is required for the development of improved treatment strategies, very few cancer patients participate in these studies. The purpose of this study was to describe psychosocial barriers to clinical trial participation among oncologists and their cancer patients. A survey was distributed to all medical oncologists in Pennsylvania and a subset of their patients. Relevant background information and assessment of practical and psychosocial barriers to clinical trial participation were assessed. Among 137 oncologists and 170 patients who completed the surveys, 84% of patients were aware of clinical trials, and oncologists and patients generally agreed that clinical trials are important to improving cancer treatment. However, oncologists and patients were more likely to consider clinical trials in advanced or refractory disease. When considering 7 potential barriers to clinical trials, random assignment and fear of receiving a placebo were ranked highly by both patients and oncologists. Patients identified fear of side effects as the greatest barrier to clinical trial participation, whereas oncologists ranked this psychosocial barrier as least important to their patients. Overall, the study found that although oncologists and patients are aware of clinical trials and have favorable attitudes toward them, psychosocial barriers exist for patients that may impact participation in clinical trials. Furthermore, important discrepancies exist between the perceptions of oncologists and those of patients regarding what the psychosocial barriers are. We concluded that characterizing oncologist and patient perceived barriers can help improve communication and decision making about clinical trials, such that participation may be optimized.

Barriers to clinical trial participation as perceived by oncologists and patients. Publishing Authors By Initials

NJ Meropol,JS Buzaglo,J Millard,N Damjanov,SM Miller,C Ridgway,EA Ross,JD Sprandio,P Watts,NJ Meropol,JS Buzaglo,J Millard,N Damjanov,SM Miller,C Ridgway,EA Ross,JD Sprandio,P Watts,

For similar investigative techniques: epidemiologic methods: data collection: questionnaires research abstracts see: investigative techniques: epidemiologic methods: data collection: questionnaires research

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Barriers to clinical trial participation as perceived by oncologists and patients. Journal Published:

PUBLICATION TYPE: Research Support, Non-U.S. Gov

Journal: Journal of the National Comprehensive Cancer Netwo

VOLUME: 5

Page Numbers: 655-64

Journal Abbreviation:

ISSN: 1540-1405

DAY: 27

MONTH: Sep

YEAR: 2007

Barriers to clinical trial participation as perceived by oncologists and patients. Information

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LANGUAGE: eng

NlmUniqueID: 101162515

Barriers to clinical trial participation as perceived by oncologists and patients. Keywords Mesh Terms:

KEYWORDS: Questionnaires

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Grant and Affiliation Information for Barriers to clinical trial participation as perceived by oncologists and patients.

AFFILIATION: Divisions of Medical Science, Fox Chase Cancer Center, Philadelphia, PA 19111, USA. Neal.Meropol@fccc.edu

Country: United States

AGENCY: United States PHS

GRANT: R01 82085

ACRONYM: CA

MEDLINETA: J Natl Compr Canc Netw

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