Azo compounds in colon-specific drug delivery.

Azo compounds in colon-specific drug delivery. Research Abstract Details

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Azo compounds in colon-specific drug delivery. Abstract Text:

Marta Roldo,Eugen Barbu,James F Brown,David W Laight,John D Smart,John Tsibouklis,

Azo compounds have the potential to act as drug carriers that facilitate the selective release of therapeutic agents to the colon, and also to effect the oral administration of those macromolecular drugs that require colon-specific drug delivery. With some further research-driven refinements, these materials may lead to more efficient treatments for local conditions, such as colonic cancer or inflammatory bowel disease. This article provides an overview of the azo-based systems developed to date, identifies the requirements for an ideal carrier, and highlights the directions for further developments in the field of azo group-facilitated colonic delivery.

Azo compounds in colon-specific drug delivery. Publishing Authors By Initials

M Roldo,E Barbu,JF Brown,DW Laight,JD Smart,J Tsibouklis,

For similar pharmaceutical preparations: prodrugs research abstracts see: pharmaceutical preparations: prodrugs research

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Azo compounds in colon-specific drug delivery. Journal Published:

PUBLICATION TYPE: Review

Journal: Expert opinion on drug delivery

VOLUME: 4

Page Numbers: 547-60

Journal Abbreviation:

ISSN: 1742-5247

DAY: 29

MONTH: Sep

YEAR: 2007

Azo compounds in colon-specific drug delivery. Information

Number of References: 113

LANGUAGE: eng

NlmUniqueID: 101228421

Azo compounds in colon-specific drug delivery. Keywords Mesh Terms:

KEYWORDS: Prodrugs

MESH TERMS: chemistry

Chemical & Substance for Abstract: Azo compounds in colon-specific drug delivery. Information

Substance Name: Prodrugs

Registry Number: 0

Grant and Affiliation Information for Azo compounds in colon-specific drug delivery.

AFFILIATION: University of Portsmouth, School of Pharmacy and Biomedical Sciences, St Michael's Building, White Swan Road, Portsmouth PO1 2DT, UK.

Country: England