Automatic generation of steady state enzyme rate equation and the associated constraint equations.

Automatic generation of steady state enzyme rate equation and the associated constraint equations. Research Abstract Details 

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Automatic generation of steady state enzyme rate equation and the associated constraint equations. Abstract Text:

C F Lam,N Schatz,

A computer algorithm is presented to derive initial velocity rate equation for general enzyme raction mechanisms, including sequential as well as complicated random mechanisms. The method is based on the theory of graph and the theory of prime number. In complicated mechanisms, there are many pathways and hence many cycles. The values of the rate constants are constrained according to the principle of detailed balance: the product of rate constants in the clockwise direction of a cycle must equal to the product of the rate constants in the counter-clockwise direction of the same cycle. An algorithm is presented to derive the appropriate constraint equations. These constraint equations are arranged so that when the rate equation is used for estimating rate constants, the resulting rate constants would satisfy the principle of detailed balance automatically.

Automatic generation of steady state enzyme rate equation and the associated constraint equations. Publishing Authors By Initials

CF Lam,N Schatz,

For similar investigative techniques: methods research abstracts see: investigative techniques: methods research

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Automatic generation of steady state enzyme rate equation and the associated constraint equations. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Journal of biochemistry

VOLUME: 84

Page Numbers: 585-95

Journal Abbreviation: J. Biochem.

ISSN: 0021-924X

DAY: 19

MONTH: Sep

YEAR: 1978

Automatic generation of steady state enzyme rate equation and the associated constraint equations. Information

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LANGUAGE: eng

NlmUniqueID: 376600

Automatic generation of steady state enzyme rate equation and the associated constraint equations. Keywords Mesh Terms:

KEYWORDS: Methods

MESH TERMS: metabolism

Chemical & Substance for Abstract: Automatic generation of steady state enzyme rate equation and the associated constraint equations. Information

Substance Name: Enzymes

Registry Number: 0

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Country: JAPAN

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MEDLINETA: J Biochem

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