Autism spectrum disorders: developmental disconnection syndromes.

Autism spectrum disorders: developmental disconnection syndromes. Research Abstract Details 

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Autism spectrum disorders: developmental disconnection syndromes. Abstract Text:

Daniel H Geschwind,Pat Levitt,

Autism is a common and heterogeneous childhood neurodevelopmental disorder. Analogous to broad syndromes such as mental retardation, autism has many etiologies and should be considered not as a single disorder but, rather, as 'the autisms'. However, recent genetic findings, coupled with emerging anatomical and functional imaging studies, suggest a potential unifying model in which higher-order association areas of the brain that normally connect to the frontal lobe are partially disconnected during development. This concept of developmental disconnection can accommodate the specific neurobehavioral features that are observed in autism, their emergence during development, and the heterogeneity of autism etiology, behaviors and cognition.

Autism spectrum disorders: developmental disconnection syndromes. Publishing Authors By Initials

DH Geschwind,P Levitt,

For similar nervous system: neural pathways research abstracts see: nervous system: neural pathways research

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Autism spectrum disorders: developmental disconnection syndromes. Journal Published:

PUBLICATION TYPE: Review

Journal: Current opinion in neurobiology

VOLUME: 17

Page Numbers: 103-11

Journal Abbreviation: Curr. Opin. Neurobiol.

ISSN: 0959-4388

DAY: 1

MONTH: 02

YEAR: 2007

Autism spectrum disorders: developmental disconnection syndromes. Information

Number of References: 79

LANGUAGE: eng

NlmUniqueID: 9111376

Autism spectrum disorders: developmental disconnection syndromes. Keywords Mesh Terms:

KEYWORDS: Neural Pathways

MESH TERMS: physiopathology

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Grant and Affiliation Information for Autism spectrum disorders: developmental disconnection syndromes.

AFFILIATION: Program in Neurogenetics, Department of Neurology and Semel Institute, David Geffen School of Medicine at University of California Los Angeles, 710 Westwood Plaza, Los Angeles, CA 90095, USA. dhg@ucla.edu

Country: England

AGENCY: United States NIMH

GRANT: U54 MH68172

ACRONYM: MH

MEDLINETA: Curr Opin Neurobiol

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