-Gordon J Freeman Researcher Activity Profile

Research Author Detailed Information 

Gordon J Freeman Publication Rate By Year

Gordon J Freeman has published 1 paper(s) in 2006, 22 paper(s) in 2007, 3 paper(s) in 2008, for a total of 26 research publications in total.

Gordon J Gj Freeman Author Information

LAST NAME: freeman

FIRST NAME: Gordon J

INITIALS: gj

AFFILIATION:

Papers

Gordon J Freeman's Publication Record

1. Reinvigorating exhausted HIV-specific T cells via PD-1-PD-1 ligand blockade. Year Published: 2006
Department of Medical Oncology, Dana-Farber Cancer Institute, Department of Medicine, Harvard Medical School, Boston, MA 02115, USA. gordon_freeman@dfci.harvard.edu
2. PD-1:PD-L1 interactions contribute to the functional suppression of virus-specific CD8+ T lymphocytes in the liver. Year Published: 2007
Department of Molecular and Experimental Medicine, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA.
3. Immunoglobulin A (IgA) is a natural ligand of hepatitis A virus cellular receptor 1 (HAVCR1), and the association of IgA with HAVCR1 enhances virus-receptor interactions. Year Published: 2007
Laboratory of Hepatitis and Related Emerging Agents, CBER, Food and Drug Administration, Bethesda, MD 20892, USA.
4. Twisted gastrulation (Tsg) is regulated by Tob and enhances TGF-beta signaling in activated T lymphocytes. Year Published: 2007
Department of Hematology and Oncology, Beth Israel-Deaconess Medical Center, Boston, MA, USA.
5. Elevated expression levels of inhibitory receptor programmed death 1 on simian immunodeficiency virus-specific CD8 T cells during chronic infection but not after vaccination. Year Published: 2007
Vaccine Research Center, Department of Microbiology and Immunology, Yerkes National Primate Research Center, Emory University, Atlanta, Georgia 30329, USA.
6. A novel alloantigen-specific CD8+PD1+ regulatory T cell induced by ICOS-B7h blockade in vivo. Year Published: 2007
Transplantation Research Center, Renal Division, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.
7. Programmed death-1 ligand 1 interacts specifically with the B7-1 costimulatory molecule to inhibit T cell responses. Year Published: 2007
Department of Pathology, Harvard Medical School, Boston, MA 02115, USA.
8. PD-1 expression on human CD8 T cells depends on both state of differentiation and activation status. Year Published: 2007
9. Viral targeting of fibroblastic reticular cells contributes to immunosuppression and persistence during chronic infection. Year Published: 2007
Emory Vaccine Center and Department of Microbiology and Immunology, Emory University, Atlanta, GA 30322, USA.
10. In-fusion assembly: seamless engineering of multidomain fusion proteins, modular vectors, and mutations. Year Published: 2007
Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA 02115, USA.
11. PD-1 regulates self-reactive CD8+ T cell responses to antigen in lymph nodes and tissues. Year Published: 2007
Department of Pathology, Harvard Medical School and Brigham and Women's Hospital, Boston, MA 02115, USA.
12. Upregulation of CTLA-4 by HIV-specific CD4(+) T cells correlates with disease progression and defines a reversible immune dysfunction. Year Published: 2007
[1] Partners AIDS Research Center, Massachusetts General Hospital and Division of AIDS, Harvard Medical School, Boston, Massachusetts 02115, USA. [2] These authors contributed equally to this work.
13. Endothelial programmed death-1 ligand 1 (PD-L1) regulates CD8+ T-cell mediated injury in the heart. Year Published: 2007
Department of Pathology, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115, USA.
14. Endothelial programmed death-1 ligand 1 (PD-L1) regulates CD8+ T-cell mediated injury in the heart. Year Published: 2007
Department of Pathology, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115, USA.
15. TIM-1 and TIM-4 Glycoproteins Bind Phosphatidylserine and Mediate Uptake of Apoptotic Cells. Year Published: 2007
Department of Medical Oncology, Dana-Farber Cancer Institute, 44 Binney Street, and Department of Medicine, Harvard Medical School, Boston, MA 02115, USA.
16. Structures of T Cell Immunoglobulin Mucin Protein 4 Show a Metal-Ion-Dependent Ligand Binding Site where Phosphatidylserine Binds. Year Published: 2007
17. Upregulation of CTLA-4 by HIV-specific CD4+ T cells correlates with disease progression and defines a reversible immune dysfunction. Year Published: 2007
Partners AIDS Research Center, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA. dkaufmann@partners.org
18. Upregulation of CTLA-4 by HIV-specific CD4+ T cells correlates with disease progression and defines a reversible immune dysfunction. Year Published: 2007
Partners AIDS Research Center, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA. dkaufmann@partners.org
19. CD160 inhibits activation of human CD4+ T cells through interaction with herpesvirus entry mediator. Year Published: 2008
Department of Medical Oncology, Dana-Farber Cancer Institute, Department of Medicine, Harvard Medical School, Boston, Massachusetts 02115, USA.
20. TIM-1 and TIM-4 glycoproteins bind phosphatidylserine and mediate uptake of apoptotic cells. Year Published: 2007
Department of Medical Oncology, Dana-Farber Cancer Institute, 44 Binney Street, Harvard Medical School, Boston, MA 02115, USA.
21. Structures of T cell immunoglobulin mucin protein 4 show a metal-Ion-dependent ligand binding site where phosphatidylserine binds. Year Published: 2007
22. TIM-1 and TIM-4 glycoproteins bind phosphatidylserine and mediate uptake of apoptotic cells. Year Published: 2007
Department of Medical Oncology, Dana-Farber Cancer Institute, 44 Binney Street, Harvard Medical School, Boston, MA 02115, USA.
23. Structures of T cell immunoglobulin mucin protein 4 show a metal-Ion-dependent ligand binding site where phosphatidylserine binds. Year Published: 2007
Centro Nacional de Biotecnología, CSIC, Campus Universidad Autónoma, 28049 Madrid, Spain.
24. The PD-1/PD-L costimulatory pathway critically affects host resistance to the pathogenic fungus Histoplasma capsulatum. Year Published: 2008
Departments of Microbiology and Immunology, Cell Biology, Medicine, Biochemistry, and Physiology and Biophysics, Albert Einstein College of Medicine, Yeshiva University, 1300 Morris Park Avenue, Bronx, NY 10461.
25. PD-1 expression on human CD8 T cells depends on both state of differentiation and activation status. Year Published: 2007
26. Enhancing therapeutic vaccination by blocking PD-1-mediated inhibitory signals during chronic infection. Year Published: 2008
Emory Vaccine Center and Department of Microbiology and Immunology, Emory University School of Medicine, Atlanta, GA 30322, USA.