Augmentation of pulmonary vein backflow velocity during left atrial contraction: a novel phenomenon responsible for progression of atrial fibrillation in hypertensive patients.

Augmentation of pulmonary vein backflow velocity during left atrial contraction: a novel phenomenon responsible for progression of atrial fibrillation in hypertensive patients. Research Abstract Details 

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Augmentation of pulmonary vein backflow velocity during left atrial contraction: a novel phenomenon responsible for progression of atrial fibrillation in hypertensive patients. Abstract Text:

Toru Maruyama,Toshisuke Kishikawa,Hiroyuki Ito,Yoshikazu Kaji,Yasushi Sasaki,Yasushi Ishihara,Toru Maruyama,Toshisuke Kishikawa,Hiroyuki Ito,Yoshikazu Kaji,Yasushi Sasaki,Yasushi Ishihara,

BACKGROUND: Atrial fibrillation (AF) is a common arrhythmia showing disease progression. However, echocardiographic prediction of such progression remains incomplete. This study aimed to identify echocardiographic predictors of AF progression in hypertensive patients. METHODS: Hypertensive patients with paroxysmal AF were divided into two groups: patients with AF which became permanent (group A; n = 13) and those with AF which remained paroxysmal (group B; n = 46) during the same follow-up period (8.0 +/- 2.4 years). Clinical baselines showed no significant differences except for age. Transthoracic echocardiography was recorded 1-2 weeks after termination of the first-detected paroxysms of AF. RESULTS: Echocardiography showed greater left atrial (LA) dimension (p = 0.023) and late diastolic pulmonary vein (PV) backflow velocity (p < 0.001), and a lower LA fractional shortening (p = 0.008) in group A than in group B. Multilogistic regression analysis demonstrated that augmented PV backflow (p = 0.007) and reduced LA fractional shortening (p = 0.032) were independent predictors of the progression of AF. The receiver-operating characteristic curve demonstrated that PV backflow augmentation is the best predictor of future AF perpetuation. CONCLUSION: PV backflow leading to cyclic stretching of PV musculature contributes to AF progression.

Augmentation of pulmonary vein backflow velocity during left atrial contraction: a novel phenomenon responsible for progression of atrial fibrillation in hypertensive patients. Publishing Authors By Initials

T Maruyama,T Kishikawa,H Ito,Y Kaji,Y Sasaki,Y Ishihara,T Maruyama,T Kishikawa,H Ito,Y Kaji,Y Sasaki,Y Ishihara,

For similar cardiovascular system: blood vessels: veins: pulmonary veins research abstracts see: cardiovascular system: blood vessels: veins: pulmonary veins research

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Augmentation of pulmonary vein backflow velocity during left atrial contraction: a novel phenomenon responsible for progression of atrial fibrillation in hypertensive patients. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Cardiology

VOLUME: 109

Page Numbers: 33-40

Journal Abbreviation: Cardiology

ISSN: 1421-9751

DAY: 10

MONTH: 07

YEAR: 2007

Augmentation of pulmonary vein backflow velocity during left atrial contraction: a novel phenomenon responsible for progression of atrial fibrillation in hypertensive patients. Information

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LANGUAGE: eng

NlmUniqueID: 1266406

Augmentation of pulmonary vein backflow velocity during left atrial contraction: a novel phenomenon responsible for progression of atrial fibrillation in hypertensive patients. Keywords Mesh Terms:

KEYWORDS: Pulmonary Veins

MESH TERMS: physiopathology

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Grant and Affiliation Information for Augmentation of pulmonary vein backflow velocity during left atrial contraction: a novel phenomenon responsible for progression of atrial fibrillation in hypertensive patients.

AFFILIATION: Department of Medicine, Kyushu University, Fukuoka, Japan. maruyama@ihs.kyushu-u.ac.jp

Country: Switzerland

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MEDLINETA: Cardiology

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