Atypical neural substrates of Embedded Figures Task performance in children with Autism Spectrum Disorder.

Atypical neural substrates of Embedded Figures Task performance in children with Autism Spectrum Disorder. Research Abstract Details 

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Atypical neural substrates of Embedded Figures Task performance in children with Autism Spectrum Disorder. Abstract Text:

Philip S Lee,Jennifer Foss-Feig,Joshua G Henderson,Lauren E Kenworthy,Lisa Gilotty,William D Gaillard,Chandan J Vaidya,

Superior performance on the Embedded Figures Task (EFT) has been attributed to weak central coherence in perceptual processing in Autism Spectrum Disorder (ASD). The present study used functional magnetic resonance imaging to examine the neural basis of EFT performance in 7- to 12-year-old ASD children and age- and IQ-matched controls. ASD children activated only a subset of the distributed network of regions activated in controls. In frontal cortex, control children activated left dorsolateral, medial and dorsal premotor regions whereas ASD children only activated the dorsal premotor region. In parietal and occipital cortices, activation was bilateral in control children but unilateral (left superior parietal and right occipital) in ASD children. Further, extensive bilateral ventral temporal activation was observed in control, but not ASD children. ASD children performed the EFT at the same level as controls but with reduced cortical involvement, suggesting that disembedded visual processing is accomplished parsimoniously by ASD relative to typically developing brains.

Atypical neural substrates of Embedded Figures Task performance in children with Autism Spectrum Disorder. Publishing Authors By Initials

PS Lee,J Foss-Feig,JG Henderson,LE Kenworthy,L Gilotty,WD Gaillard,CJ Vaidya,

For similar psychological phenomena and processes: psychology, applied: human engineering: task performance and analysis research abstracts see: psychological phenomena and processes: psychology, applied: human engineering: task performance and analysis research

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Atypical neural substrates of Embedded Figures Task performance in children with Autism Spectrum Disorder. Journal Published:

PUBLICATION TYPE: Research Support, Non-U.S. Gov

Journal: NeuroImage

VOLUME: 38

Page Numbers: 184-93

Journal Abbreviation: Neuroimage

ISSN: 1053-8119

DAY: 24

MONTH: 07

YEAR: 2007

Atypical neural substrates of Embedded Figures Task performance in children with Autism Spectrum Disorder. Information

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LANGUAGE: eng

NlmUniqueID: 9215515

Atypical neural substrates of Embedded Figures Task performance in children with Autism Spectrum Disorder. Keywords Mesh Terms:

KEYWORDS: Task Performance and Analysis

MESH TERMS: methods

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Grant and Affiliation Information for Atypical neural substrates of Embedded Figures Task performance in children with Autism Spectrum Disorder.

AFFILIATION: Department of Psychology, Georgetown University, Washington, DC 20057, USA. cjv2@georgetown.edu

Country: United States

AGENCY: United States NCRR

GRANT: M01 RR020359-03

ACRONYM: RR

MEDLINETA: Neuroimage

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