Associations of adiponectin with sex hormone-binding globulin levels in aging male and female populations.

Associations of adiponectin with sex hormone-binding globulin levels in aging male and female populations. Research Abstract Details 

Research Abstract Table of Contents

Jump to the:

Associations of adiponectin with sex hormone-binding globulin levels in aging male and female populations. Abstract Text:

Toshiyuki Yasui,Junko Tomita,Yuka Miyatani,Masayo Yamada,Hirokazu Uemura,Minoru Irahara,Makoto Arai,Noriko Kojimahara,Ryugo Okabe,Yasutomo Ishii,Shin-ichi Tashiro,Hiroshi Sato,Toshiyuki Yasui,Junko Tomita,Yuka Miyatani,Masayo Yamada,Hirokazu Uemura,Minoru Irahara,Makoto Arai,Noriko Kojimahara,Ryugo Okabe,Yasutomo Ishii,Shin-ichi Tashiro,Hiroshi Sato,

BACKGROUND: Changes with aging in serum gonadal hormones, sex hormone-binding globulin (SHBG) and adiponectin, which are involved in insulin resistance and metabolic syndrome, are different in men and women. We examined the relationships of serum adiponectin concentrations with serum concentrations of hormones and SHBG in men and women. METHODS: One hundred fifty-four men and 180 women aged from 50 to 85 years were included in the cross-sectional study. Serum concentrations of testosterone, estradiol, dehydroepiandrosterone-sulfate, SHBG and adiponectin were measured in men and women. RESULTS: Serum adiponectin concentration showed a significant positive correlation with serum SHBG concentration in men and women (r=0.404, p<0.0001 and r=0.348, p<0.0001, respectively). Multiple regression analysis also showed that SHBG was the significant predictor for adiponectin in men and women. Serum adiponectin concentration in men showed a significant positive correlation with total testosterone concentration, but that in women was not significantly correlated with total testosterone concentration. Both adiponectin and SHBG concentrations in men (r=-0.222, p=0.0051 and r=-0.334, p<0.0001, respectively) and women (r=-0.281, p=0.0014 and r=-0.251, p=0.0048, respectively) showed significant negative correlations with the homeostasis model assessment (HOMA) index. CONCLUSION: Correlations between adiponectin and SHBG were significantly positive in both men and women, and both adiponectin and SHBG might be involved in insulin resistance in both sexes.

Associations of adiponectin with sex hormone-binding globulin levels in aging male and female populations. Publishing Authors By Initials

T Yasui,J Tomita,Y Miyatani,M Yamada,H Uemura,M Irahara,M Arai,N Kojimahara,R Okabe,Y Ishii,S Tashiro,H Sato,T Yasui,J Tomita,Y Miyatani,M Yamada,H Uemura,M Irahara,M Arai,N Kojimahara,R Okabe,Y Ishii,S Tashiro,H Sato,

For similar abstracts research abstracts see: abstracts research

PUBMED ID PMID:

MEDLINE DATE:

Associations of adiponectin with sex hormone-binding globulin levels in aging male and female populations. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Clinica chimica acta; international journal of cli

VOLUME: 386

Page Numbers: 69-75

Journal Abbreviation: Clin. Chim. Acta

ISSN: 0009-8981

DAY: 14

MONTH: 08

YEAR: 2007

Associations of adiponectin with sex hormone-binding globulin levels in aging male and female populations. Information

Number of References:

LANGUAGE: eng

NlmUniqueID: 1302422

Associations of adiponectin with sex hormone-binding globulin levels in aging male and female populations. Keywords Mesh Terms:

KEYWORDS:

MESH TERMS:

Chemical & Substance for Abstract: Associations of adiponectin with sex hormone-binding globulin levels in aging male and female populations. Information

Substance Name:

Registry Number:

Grant and Affiliation Information for Associations of adiponectin with sex hormone-binding globulin levels in aging male and female populations.

AFFILIATION: Department of Obstetrics and Gynecology, Institute of Health Biosciences, The University of Tokushima Graduate School, Tokushima 770-8503, Japan. yasui@clin.med.tokushima-u.ac.jp

Country: Netherlands

AGENCY:

GRANT:

ACRONYM:

MEDLINETA: Clin Chim Acta

REFSOURCE:

DATABASENAME:

ACCESSION NUMBER:

Number Hits: 0

Associations of adiponectin with sex hormone-binding globulin levels in aging male and female populations Related Publications

• Age related changes in the distribution of laryngeal glands in the human adult larynx.
• Anti-eosinophil peroxidase antibodies detected in patients with primary biliary cirrhosis.
• Assessment of bull fertility using a mucus penetration test and a human chorionic gonadotrophin stimulation test.
• Colonic mucosal lesions associated with long-term administration of non-steroidal anti-inflammatory drugs.
• Decreased expression levels of CD22 and L-selectin on peripheral blood B lymphocytes from patients with bullous pemphigoid.
• Differences in acetazolamide vasoreactivity in patients with acute and chronic occlusion of the internal carotid artery.
• Effect of low-molecular-weight heparin on the commitment of bone marrow cells to liver sinusoidal endothelial cells in CCl(4)-induced liver injury.
• Effects of gonadotropin releasing hormone and prostaglandin F(2)alpha on the reproductive performance in postpartum cows.
• Exacerbation of dietary steatohepatitis and fibrosis in obese, diabetic KK-A(y) mice.
• Expression of MUC1 and MUC2 mucin antigens in intrahepatic bile duct tumors: its relationship with a new morphological classification of cholangiocarcinoma.
• Expression of MUC1 and MUC2 mucins in gastric carcinomas: its relationship with the prognosis of the patients.
• Expression of mucin antigens in human cancers and its relationship with malignancy potential.
• Gene expression of gastric type mucin (MUC5AC) in pancreatic tumors: its relationship with the biological behavior of the tumor.
• Hepatic steatosis is a predictor of poor response to interferon alpha-2b and ribavirin combination therapy in Japanese patients with chronic hepatitis C.
• Immunohistochemical study of mucin carbohydrates and core proteins in human pancreatic tumors.
• Infective Endocarditis Associated with Sjogren's Syndrome.
• Isokinetic external rotation strength of shoulder : correlation with age and muscle size.
• MUC-1 mucin expression in invasive areas of intraductal papillary mucinous tumors of the pancreas.
• MUC2 gene expression is found in noninvasive tumors but not in invasive tumors of the pancreas and liver: its close relationship with prognosis of the patients.
• Mechanism by which Bombyx mori hemocytes recognize microorganisms: direct and indirect recognition systems for PAMPs.
• Modeling of daily operation in proton radiotherapy by Monte Carlo method.
• Mucin antigen expression in gastric carcinomas of young and old adults.
• Prostaglandin E(2) levels in uterine tissues and its relationship with uterine and luteal progesterone during the estrous cycle in dairy cows.
• Reconstruction of scalp and cranium defect utilizing latissimus dorsi musculocutaneous and serratus anterior muscle free flaps with interpositional anastomosis of T-shaped flap artery: case report.
• Second messenger systems mediating sex pheromone and amino Acid sensitivity in goldfish olfactory receptor neurons.
• Study on the appearance of the cavity in the corpus luteum of cows by using ultrasonic scanning.
• The expression of several types of mucin is related to the biological behavior of pancreatic neoplasms.
• The role of leptin in progression of non-alcoholic fatty liver disease.
• Voglibose potentiates the hepatotoxicity of carbon tetrachloride and acetaminophen by inducing CYP2E1 in rats.
• [Development and operation of cultured cell experiment with TR-IA sounding rocket]