Association of vitamin D receptor polymorphism with calcaneal broadband ultrasound attenuation in Korean postmenopausal women with low calcium intake.

Association of vitamin D receptor polymorphism with calcaneal broadband ultrasound attenuation in Korean postmenopausal women with low calcium intake. Research Abstract Details 

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Association of vitamin D receptor polymorphism with calcaneal broadband ultrasound attenuation in Korean postmenopausal women with low calcium intake. Abstract Text:

Hee-Seon Kim,Ji-Sun Kim,Nam Soo Kim,Jin Ho Kim,Byung-Kook Lee,Hee-Seon Kim,Ji-Sun Kim,Nam Soo Kim,Jin Ho Kim,Byung-Kook Lee,Hee-Seon Kim,Ji-Sun Kim,Nam Soo Kim,Jin Ho Kim,Byung-Kook Lee,

This study investigated the associations among vitamin D receptor (VDR) BsmI polymorphism, calcium intake and bone strength as indicated by the broadband ultrasound attenuation (BUA) measured by calcaneal quantitative ultrasound at the left calcaneus in community-dwelling subjects with a low calcium intake. The VDR BsmI polymorphism was analysed in 335 women older than 65 years residing in rural Asan, Korea. Calcium intake was assessed with a 2 d, 24 h recall method. The distribution of genotypes was similar to that reported in other Asian populations (92 % bb, 7 % Bb and 1 % BB). The calcaneal BUA was significantly higher (P = 0.013) in the bb genotype than in the Bb or BB genotype (Bb and BB genotypes were combined due to the small number of BB subjects) in a multiple regression model after adjusting for age, body weight, height, physical activity and nutritional factors. BUA was not significantly affected by the calcium intake regardless of the genotype, cross-sectionally. The energy-adjusted average calcium intake of this population was 439.6 mg/d (432.5 mg/d for bb and 522.3 mg/d for Bb or BB), and 96 % of the subjects had dietary intakes that were less than the recommended Dietary Reference Intake for Koreans (which for calcium is 800 mg/d for women older than 65 years). In summary, the BUA in older Korean women with a low calcium intake was significantly influenced by the VDR genotype but not by the calcium intake, cross-sectionally.

Association of vitamin D receptor polymorphism with calcaneal broadband ultrasound attenuation in Korean postmenopausal women with low calcium intake. Publishing Authors By Initials

HS Kim,JS Kim,NS Kim,JH Kim,BK Lee,HS Kim,JS Kim,NS Kim,JH Kim,BK Lee,HS Kim,JS Kim,NS Kim,JH Kim,BK Lee,

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Association of vitamin D receptor polymorphism with calcaneal broadband ultrasound attenuation in Korean postmenopausal women with low calcium intake. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: The British journal of nutrition

VOLUME: 98

Page Numbers: 878-81

Journal Abbreviation: Br. J. Nutr.

ISSN: 0007-1145

DAY: 12

MONTH: 06

YEAR: 2007

Association of vitamin D receptor polymorphism with calcaneal broadband ultrasound attenuation in Korean postmenopausal women with low calcium intake. Information

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LANGUAGE: eng

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Grant and Affiliation Information for Association of vitamin D receptor polymorphism with calcaneal broadband ultrasound attenuation in Korean postmenopausal women with low calcium intake.

AFFILIATION: Department of Food Science and Nutrition, Soonchunhyang University, Asan, 336-745, Republic of Korea.

Country: England

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MEDLINETA: Br J Nutr

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