Association between Strongyloides stercoralis infection and biliary tract cancer.

Association between Strongyloides stercoralis infection and biliary tract cancer. Research Abstract Details 

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Association between Strongyloides stercoralis infection and biliary tract cancer. Abstract Text:

Tetsuo Hirata,Kazuto Kishimoto,Nagisa Kinjo,Akira Hokama,Fukunori Kinjo,Jiro Fujita,Tetsuo Hirata,Kazuto Kishimoto,Nagisa Kinjo,Akira Hokama,Fukunori Kinjo,Jiro Fujita,Tetsuo Hirata,Kazuto Kishimoto,Nagisa Kinjo,Akira Hokama,Fukunori Kinjo,Jiro Fujita,

Infectious agents, including parasites, often have oncogenic potential. However, there has been no study on the association between Strongyloides stercoralis infection and cancer risk. Therefore, we investigated the relationship between S. stercoralis infection and the occurrence of hepato-pancreato-biliary cancer. This case-control study examined 1,654 patients aged >/=50 years in the Department of Medicine and Therapeutics, Ryukyu University Hospital, Okinawa, Japan, between 1991 and 2005. There were 196 patients with hepato-pancreato-biliary cancer and 1,458 control patients without cancer. The association between S. stercoralis infection and cancer was analyzed by logistic regression analysis adjusted for human T cell lymphotropic virus type 1 infection, age, and sex. The prevalence of S. stercoralis infection in controls and biliary tract cancer was significantly different at 7.5 and 18.4%, respectively (P = 0.03, adjusted odds ratio 2.7, 95% confidence intervals 1.1-6.3). In conclusion, our study indicates that the prevalence of S. stercoralis infection in patients with biliary tract cancer appears significantly higher than that in control patients. Thus, we propose that S. stercoralis infection is a risk factor for biliary tract cancer.

Association between Strongyloides stercoralis infection and biliary tract cancer. Publishing Authors By Initials

T Hirata,K Kishimoto,N Kinjo,A Hokama,F Kinjo,J Fujita,T Hirata,K Kishimoto,N Kinjo,A Hokama,F Kinjo,J Fujita,T Hirata,K Kishimoto,N Kinjo,A Hokama,F Kinjo,J Fujita,

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Association between Strongyloides stercoralis infection and biliary tract cancer. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Parasitology research

VOLUME: 101

Page Numbers: 1345-8

Journal Abbreviation: Parasitol. Res.

ISSN: 0932-0113

DAY: 5

MONTH: 07

YEAR: 2007

Association between Strongyloides stercoralis infection and biliary tract cancer. Information

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LANGUAGE: eng

NlmUniqueID: 8703571

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Grant and Affiliation Information for Association between Strongyloides stercoralis infection and biliary tract cancer.

AFFILIATION: Department of Medicine and Therapeutics,Control and Prevention of Infectious Diseases,Faculty of Medicine, University of the Ryukyus, 207 Uehara, Nishihara, Okinawa, Japan, h400314@med.u-ryukyu.ac.jp.

Country: Germany

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MEDLINETA: Parasitol Res

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