Association between Helicobacter pylori concentration and the combining frequency of histopathological findings in gastric biopsies specimens.

Association between Helicobacter pylori concentration and the combining frequency of histopathological findings in gastric biopsies specimens. Research Abstract Details 

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Association between Helicobacter pylori concentration and the combining frequency of histopathological findings in gastric biopsies specimens. Abstract Text:

Gisele Alborghetti Nai,Ana Carolina Gomes Parizi, Barbosa,

BACKGROUND: Helicobacter pylori is the most prevalent infectious agent worldwide. About 90% of patients with chronic gastritis are infected with this bacterium. Some studies have shown a association between the H. pylori concentration and the scores of gastritis activity and severity. AIM: To evaluate the association between H. pylori concentration and the combining frequency of findings on histopathological examination. METHODS: Two hundred consecutive gastric endoscopic biopsies diagnosed as chronic gastritis were retrospectively investigated. The Warthin-Starry silver stain was used to study H. pylori and the following parameters were assessed (according to the Sydney system): 1. infiltration by polymorphonuclear cells in chorio and epithelium (activity) graded as mild, moderate and marked; 2. presence of lymphoid follicles; 3. presence of intestinal metaplasia; 4. presence of regenerative cell atypias, graded as mild, moderate and marked; and 5. H. pylori concentration on the mucous covering the foveolar epithelium. RESULTS: The most frequent association was chronic gastritis and activity, regardless of H. pylori concentration. The association of five histopathological findings in the same biopsy has not occurred in the cases of higher concentration of H. pylori. CONCLUSION: Our study has not revealed any association between H. pylori concentration and an increasing in the number of histopathological findings found in the gastric mucosa. Since referring to its presence is much more important than to its concentration.

Association between Helicobacter pylori concentration and the combining frequency of histopathological findings in gastric biopsies specimens. Publishing Authors By Initials

GA Nai,AC Parizi,RL Barbosa,

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PUBMED ID PMID:

MEDLINE DATE: 2007 Jul-Sep

Association between Helicobacter pylori concentration and the combining frequency of histopathological findings in gastric biopsies specimens. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Arquivos de gastroenterologia

VOLUME: 44

Page Numbers: 240-3

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ISSN: 0004-2803

DAY: 6

MONTH: 12

YEAR: 2007

Association between Helicobacter pylori concentration and the combining frequency of histopathological findings in gastric biopsies specimens. Information

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LANGUAGE: eng

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Grant and Affiliation Information for Association between Helicobacter pylori concentration and the combining frequency of histopathological findings in gastric biopsies specimens.

AFFILIATION: Department of Pathology, Paulista West University - UNOESTE, Prudente, SP. patologia@unoeste.br

Country: Brazil

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MEDLINETA: Arq Gastroenterol

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