Assessments by patients with schizophrenia and psychiatrists of relative risk of research procedures.

Assessments by patients with schizophrenia and psychiatrists of relative risk of research procedures. Research Abstract Details 

Research Abstract Table of Contents

Jump to the:

Assessments by patients with schizophrenia and psychiatrists of relative risk of research procedures. Abstract Text:

Laura Weiss Roberts,Teddy D Warner,Katherine Green Hammond,Laura B Dunn,

OBJECTIVE: Schizophrenia studies involve diverse procedures with varying levels of risk. Federal regulations indicate that oversight of these protocols entails assessment of risk in relation to the risks encountered in everyday life. No data exist on comparing assessments of people with schizophrenia with those of psychiatrists regarding research procedure risks in relation to the usual risks of living with schizophrenia. METHODS: Structured interviews were given to 43 people with schizophrenia and a parallel written survey was given to 68 psychiatrists to compare assessments of relative risk. Twelve research procedures were rated to compare the risk of the procedure with everyday risks. Possible scores range from 1, much less risk, to 3, about the same, to 5, much more risk. RESULTS: People with schizophrenia and psychiatrists viewed filling out questionnaires, drawing a tube of blood, drawing a tube of blood for a genetic test, and having X-rays of the head as being less risky than usual daily risks. Psychiatrists saw showing a word or picture that is upsetting as being less risky than usual daily risks. In contrast, patients saw having a spinal tap, getting a new experimental medication, getting a medication that causes temporary symptoms of schizophrenia, and stopping usual medications for two weeks as being significantly more risky than usual daily risks, but psychiatrists rated only stopping usual medications for two weeks as being more risky than usual daily risks. CONCLUSIONS: Substantial congruence exists between patients and psychiatrists regarding their views of research procedure risks. Further work is needed to determine how these assessments may be used in evaluating protocols.

Assessments by patients with schizophrenia and psychiatrists of relative risk of research procedures. Publishing Authors By Initials

LW Roberts,TD Warner,KG Hammond,LB Dunn,

For similar behavior and behavior mechanisms: behavior: health behavior: treatment refusal research abstracts see: behavior and behavior mechanisms: behavior: health behavior: treatment refusal research

PUBMED ID PMID:

MEDLINE DATE:

Assessments by patients with schizophrenia and psychiatrists of relative risk of research procedures. Journal Published:

PUBLICATION TYPE: Research Support, N.I.H., Extr

Journal: Psychiatric services (Washington, D.C.)

VOLUME: 57

Page Numbers: 1629-35

Journal Abbreviation:

ISSN: 1075-2730

DAY: 3

MONTH: Nov

YEAR: 2006

Assessments by patients with schizophrenia and psychiatrists of relative risk of research procedures. Information

Number of References:

LANGUAGE: eng

NlmUniqueID: 9502838

Assessments by patients with schizophrenia and psychiatrists of relative risk of research procedures. Keywords Mesh Terms:

KEYWORDS: Treatment Refusal

MESH TERMS: statistics & numerical data

Chemical & Substance for Abstract: Assessments by patients with schizophrenia and psychiatrists of relative risk of research procedures. Information

Substance Name:

Registry Number:

Grant and Affiliation Information for Assessments by patients with schizophrenia and psychiatrists of relative risk of research procedures.

AFFILIATION: Department of Psychiatry and Behavioral Medicine, Medical College of Wisconsin, 3rd Floor Tosa Center, 1155 North Mayfair Road, Milwaukee, WI 53226, USA. robertsl@mcw.edu

Country: United States

AGENCY: United States NIMH

GRANT: K23 MH 66062

ACRONYM: MH

MEDLINETA: Psychiatr Serv

REFSOURCE:

DATABASENAME:

ACCESSION NUMBER:

Number Hits: 0

Assessments by patients with schizophrenia and psychiatrists of relative risk of research procedures Related Publications

• A keystone ant species promotes seed dispersal in a "diffuse" mutualism.
• Alcohol expectancies for social facilitation: A short form with decreased bias.
• Allosteric regulation of substrate channeling in tryptophan synthase: modulation of the L-serine reaction in stage I of the beta-reaction by alpha-site ligands.
• Allosteric regulation of tryptophan synthase channeling: the internal aldimine probed by trans-3-indole-3'-acrylate binding.
• Assessments by patients with schizophrenia and psychiatrists of relative risk of research procedures.
• Audit, antithrombotics and atrial fibrillation-going full circle.
• Autophagy in the heart and liver during normal aging and calorie restriction.
• Capacity to consent to research in schizophrenia: the expanding evidence base.
• Directed differentiation of human embryonic stem cells into the pancreatic endocrine lineage.
• Effect of norgestomet on peripheral levels of progesterone and estradiol-17(beta) in beef cows.
• Effects of chronic footshock, restraint and corticotropin-releasing factor on freezing, ultrasonic vocalization and forced swim behavior in rats.
• Effects of interleukin-1beta and lipopolysaccharide on behavior of mice in the elevated plus-maze and open field tests.
• Evidence for sex ratio distortion by a new microsporidian parasite of a Corophiid amphipod.
• Expression of a novel marine viral single-chain serine palmitoyltransferase and construction of yeast and mammalian single-chain chimera.
• High-resolution studies of lung surfactant collapse.
• Measuring oxygenation in vivo with MRS/MRI--from gas exchange to the cell.
• National trend indicates women's growing representation in medicine.
• Predictors of self-reported health among older African-American central city adults.
• Proteome analysis: from protein characterization to biological function.
• Psychosocial care needs of children with recent-onset asthma.
• Relationship of nutrition to successful embryo transplantation.
• Risk factors for ocular complications and poor visual acuity at presentation among patients with uveitis associated with juvenile idiopathic arthritis.
• Salmonella transmission through splash exposure during a bovine necropsy.
• Show me the money: cost-benefit analysis in the work environment.
• Surgical and nonsurgical therapy for lung metastasis: indications and outcomes.
• Synthesis and characterization of allosteric probes of substrate channeling in the tryptophan synthase bienzyme complex.
• The management of hypertension in ischaemic heart disease.
• Total modification of the bacteriophage lambda tail tube major subunit protein with foreign peptides.
• Universal newborn screening and adverse medical outcomes: a historical note.
• Vault ribonucleoprotein particles and the central mass of the nuclear pore complex.