[Assessment of total body water of patients on hemodialysis with urea kinetic model.]

[Assessment of total body water of patients on hemodialysis with urea kinetic model.] Research Abstract Details 

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[Assessment of total body water of patients on hemodialysis with urea kinetic model.] Abstract Text:

Li Zuo,Mei Wang,Hong Wei,Jin-xia Peng,Li-li Feng,

OBJECTIVE: To propose a method to evaluate the total body water (TBW) of patients on hemodialysis with urea kinetic model (UKM), and compare it with body surface bio-impedance spectrum (BIS) analysis. METHODS: We enrolled 24 adult patients with end stage renal disease (ESRD) without hyper-catabolism in our dialysis center. All of them had been on hemodialysis for more than 3 months. TBW was measured with BIS analysis immediately before and after dialysis session, and one hour after hemodialysis session. Spent dialysate was collected; blood samples were taken before and one hour after hemodialysis session, TBW before hemodialysis session were calculated by UKM. RESULTS: Patients were 6 men and 18 women, the average age was (51.2+/-13.5) years and the average time on dialysis was (33.2+/-36.7) months. Causes of ESRD included chronic glomerulonephritis (8 patients), diabetic nephropathy (1 patients), hypertensive renal damage (1 patients), interstitial nephritis(two patients), chronic pyelonephritis (two patients). The average ultrafiltration volume was (2.7+/-1.0) L (0.5-4.4 L) . Plasma urea concentrations were (23.06+/-5.76) mmol/L and (8.15+/-2.06) mmol/L before and one hour after hemodialysis session, respectively. There was no significant difference between TBW measured immediately after and one hour after hemodialysis session with BIS analysis [(29.9+/-8.8) L and (29.8+/-8.6) L, respectively; average difference was (0.1+/-0.9)L, P=0.70]. These two measurements correlated very well (Pearson r=0.99, P<0.05). There was no significant difference between UKM and BIS analysis [(31.4+/-7.3) L and (31.3+/-8.6) L, respectively; average difference was (0.2+/-4.5) L, P=0.87]. Results of these two methods correlated very well (Pearson r=0.86, r(2)=0.73,P< 0.05). CONCLUSION: TBW measured with UKM in patients on hemodialysis provides theoretic basis for fluid status evaluation and dry body weight assessment.

[Assessment of total body water of patients on hemodialysis with urea kinetic model.] Publishing Authors By Initials

L Zuo,M Wang,H Wei,JX Peng,LL Feng,

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[Assessment of total body water of patients on hemodialysis with urea kinetic model.] Journal Published:

PUBLICATION TYPE: Research Support, Non-U.S. Gov

Journal: Beijing da xue xue bao. Yi xue ban = Journal of Pe

VOLUME: 36

Page Numbers: 533-5

Journal Abbreviation: Beijing Da Xue Xue Bao

ISSN: 1671-167X

DAY: 18

MONTH: Oct

YEAR: 2004

[Assessment of total body water of patients on hemodialysis with urea kinetic model.] Information

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LANGUAGE: chi

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AFFILIATION: Department of Nephrology, Peking University First Hospital, Beijing 100034, China. zuoli@medmail.com.cn

Country: China

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MEDLINETA: Beijing Da Xue Xue Bao

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