Assessment of myometrial invasion by endometrial carcinoma: transvaginal sonography vs contrast-enhanced MR imaging.

Assessment of myometrial invasion by endometrial carcinoma: transvaginal sonography vs contrast-enhanced MR imaging. Research Abstract Details 

Research Abstract Table of Contents

Jump to the:

Assessment of myometrial invasion by endometrial carcinoma: transvaginal sonography vs contrast-enhanced MR imaging. Abstract Text:

Y Yamashita,H Mizutani,M Torashima,M Takahashi,K Miyazaki,H Okamura,H Ushijima,H Ohtake,T Tokunaga,

OBJECTIVE. A prospective study was designed to compare transvaginal sonography with contrast-enhanced MR imaging to determine preoperatively the depth of myometrial invasion in patients with early-stage endometrial carcinoma. SUBJECTS AND METHODS. In 40 patients, findings on transvaginal sonograms, unenhanced T2-weighted MR images, and contrast-enhanced T1-weighted Mr images were compared with histologic findings. The depth of myometrial invasion was classified as stage E (tumor limited to endometrium, n = 12), stage S (superficial invasion: tumor invades up to 50% of the myometrium, n = 15), or stage D (deep invasion: tumor invades more than 50% of the myometrium, n = 13). RESULTS. Findings on transvaginal sonograms were accurate in 27 of 40 patients (accuracy, 68%); the depth of invasion was overestimated in five patients and underestimated in eight patients. The results of unenhanced T2-weighted MR images were accurate in 27 patients (accuracy, 68%), with four overestimations and nine underestimations. The results of contrast-enhanced T1-weighted MR images were accurate in 34 patients (accuracy, 85%), with five underestimations and one overestimation. In the assessment of each stage of myometrial invasion, the sensitivity and specificity of contrast-enhanced T1-weighted imaging were higher than those of T2-weighted MR imaging and transvaginal sonography. The false-positive diagnoses based on transvaginal sonograms and T2-weighted images, respectively, involved polypoid tumors (n = 4 and 2), distension of the endometrial cavity by pyometra (n = 2 and 1), the presence of myoma (n = 2 and 1), atrophy of the myometrium (n = 1 and 0), and poor tumor/myometrium contrast (n = 0 and 2). On contrast-enhanced MR images, accuracy was influenced only in a case of polypoid tumor, because tumor, endometrial cavity, and myometrium were clearly distinguished and residual myometrium was clearly visualized. With all imaging techniques, false-negative diagnoses were caused mainly by tumors with superficially spreading growth or microscopic invasion. With transvaginal sonography, infiltrative tumor also tended to be understaged (n = 3). CONCLUSION. Contrast-enhanced MR imaging is significantly superior to transvaginal sonography and unenhanced T2-weighted MR imaging for detecting myometrial invasion.

Assessment of myometrial invasion by endometrial carcinoma: transvaginal sonography vs contrast-enhanced MR imaging. Publishing Authors By Initials

Y Yamashita,H Mizutani,M Torashima,M Takahashi,K Miyazaki,H Okamura,H Ushijima,H Ohtake,T Tokunaga,

For similar investigative techniques: epidemiologic methods: statistics as topic: sensitivity and specificity research abstracts see: investigative techniques: epidemiologic methods: statistics as topic: sensitivity and specificity research

PUBMED ID PMID:

MEDLINE DATE:

Assessment of myometrial invasion by endometrial carcinoma: transvaginal sonography vs contrast-enhanced MR imaging. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: AJR. American journal of roentgenology

VOLUME: 161

Page Numbers: 595-9

Journal Abbreviation:

ISSN: 0361-803X

DAY: 15

MONTH: Sep

YEAR: 1993

Assessment of myometrial invasion by endometrial carcinoma: transvaginal sonography vs contrast-enhanced MR imaging. Information

Number of References:

LANGUAGE: eng

NlmUniqueID: 7708173

Assessment of myometrial invasion by endometrial carcinoma: transvaginal sonography vs contrast-enhanced MR imaging. Keywords Mesh Terms:

KEYWORDS: Sensitivity and Specificity

MESH TERMS: ultrasonography

Chemical & Substance for Abstract: Assessment of myometrial invasion by endometrial carcinoma: transvaginal sonography vs contrast-enhanced MR imaging. Information

Substance Name:

Registry Number:

Grant and Affiliation Information for Assessment of myometrial invasion by endometrial carcinoma: transvaginal sonography vs contrast-enhanced MR imaging.

AFFILIATION: Department of Radiology, Kumamoto University School of Medicine, Japan.

Country: UNITED STATES

AGENCY:

GRANT:

ACRONYM:

MEDLINETA: AJR Am J Roentgenol

REFSOURCE:

DATABASENAME:

ACCESSION NUMBER:

Number Hits: 0

Assessment of myometrial invasion by endometrial carcinoma: transvaginal sonography vs contrast-enhanced MR imaging Related Publications

• A role of methionine 100 in facilitating PYP(M)-decay process in the photocycle of photoactive yellow protein.
• A third photoreceptor-specific GRK found in the retina of Oryzias latipes (Japanese killifish).
• An autopsy case of obstructive jaundice due to hepatic multiple peribiliary cysts accompanying hepatolithiasis.
• Binding of oligoguanylate to scavenger receptors is required for oligonucleotides to augment NK cell activity and induce IFN.
• Construction of Three-dimensional Human Skin Model Involving Dendritic Cells and Its Application to Skin Sensitization Test.
• EEG topography recognition by neural networks.
• Evaluation of acute myocardial infarction with late enhancement pattern on MRI compared with 201Tl and 99mTc-hydroxymethylenediphosphonate (HMDP) dual single photon emission computed tomography (SPECT) images.
• Expression and phosphorylation of transferrin receptors in mitogen-activated peripheral blood lymphocytes.
• Functional expression and site-directed mutagenesis of photoactive yellow protein.
• Haplotype-specific sequence encoding the protein kinase, interferon-inducible double-stranded RNA-dependent activator in the human leukocyte antigen class II region.
• Involvement of peripheral-type benzodiazepine receptors in the intracellular transport of heme and porphyrins.
• Recoverin alters its surface properties depending on both calcium-binding and N-terminal myristoylation.
• Stathmin expression during newt retina regeneration.
• Strut fracture of a sirolimus-eluting stent at the ostium of the right coronary artery.
• Transferrin and iron uptake by rat reticulocytes.
• Unexpected death due to intestinal obstruction by a duplication cyst in an infant.
• [Cardiac tamponade during catheterization in three patients with severe valvular heart disease: emergency pericardiotomy and valve replacement (author's transl)]
• [Clinical evaluation of pulsatile flow by pulsatile bypass pump for deep hypothermia and circulatory arrest in infants]
• [Commentary by a physician. A need to respect patients' choice in therapeutic modalities]
• [Effect of complete right bundle branch block on the clinical course and a long-term follow-up after radical surgery of ventricular septal defect: with special reference to the cases with high pulmonary vascular resistance]
• [Evaluation of volatile organic compounds (VOCs) emitted from household products by small chamber test method]
• [Hemodynamic effects of dobutamine in patients with low cardiac output after open-heart surgery (author's transl)]
• [Immunotherapy of neoplasms--experimental studies]
• [Impact of air fresheners and deodorizers on the indoor total volatile organic compounds]
• [Late calcification of a Hancock tricuspid xenograft in a child (author's transl)]
• [Left ventricular rupture as a complication of mitral valve replacement--two case-reports and review of the Japanese Literature]
• [Risk assessment for arsenic to people who live in the area of arsenic-contaminated undergroundwater in Bangladesh]
• [Simultaneous determination of 9 ultraviolet absorbers in cosmetics by high-performance liquid chromatography]
• [Studies for analyzing the prohibited ingredients such as cadmium sulfide in cosmetics]
• [Studies for analyzing the prohibited ingredients such as mercury in cosmetics]