Assessment of health-related quality of life of adolescent cancer patients using the Minneapolis-Manchester Quality of Life Adolescent Questionnaire.

Assessment of health-related quality of life of adolescent cancer patients using the Minneapolis-Manchester Quality of Life Adolescent Questionnaire. Research Abstract Details 

Research Abstract Table of Contents

Jump to the:

Assessment of health-related quality of life of adolescent cancer patients using the Minneapolis-Manchester Quality of Life Adolescent Questionnaire. Abstract Text:

Eric Wu,Leslie L Robison,Meriel E M Jenney,Todd H Rockwood,James Feusner,Debra Friedman,Robert L Kane,Smita Bhatia,

BACKGROUND: Improved survival after childhood cancer has shifted the focus to health-related quality of life (HRQL)-an understudied problem, especially among adolescents. PROCEDURE: We assessed HRQL among adolescents utilizing a validated self-report tool, the Minneapolis-Manchester Quality of Life (MMQL) Adolescent Form, consisting of 46 items comprising seven domains: physical, cognitive, psychological and social functioning, body image, intimate relations, and outlook on life, and computed an overall QoL score. The MMQL Adolescent Form was administered to 226 adolescent survivors of childhood cancer a median of 7.8 years from diagnosis (off therapy-median age: 16.2 years), 136 adolescent cancer patients undergoing therapy (on therapy-median age: 16.4 years), and 134 healthy adolescents (controls-median age: 15.5 years). Primary diagnoses included leukemia (46%), lymphoma (26%), brain tumors (5%), and other solid tumors (23%). RESULTS: Compared to healthy controls, on-therapy patients were at increased risk for reporting poor overall QoL [Odds Ratio (OR) = 3.3, P = 0.002)] and poor physical functioning (OR = 11.8, P < 0.001). Off-therapy survivors did not differ significantly from healthy controls for overall QoL (OR = 1.6, P = 0.5) or any HRQL domains. Female patients, both on- and off-therapy, were more likely to report poorer overall QoL, physical, psychological and cognitive functioning as well as poorer body image when compared with male patients. CONCLUSIONS: While adolescent cancer patients undergoing active therapy report poor physical functioning, there is no evidence of long-term QoL sequelae.

Assessment of health-related quality of life of adolescent cancer patients using the Minneapolis-Manchester Quality of Life Adolescent Questionnaire. Publishing Authors By Initials

E Wu,LL Robison,ME Jenney,TH Rockwood,J Feusner,D Friedman,RL Kane,S Bhatia,

For similar geographic locations: americas: north america: united states research abstracts see: geographic locations: americas: north america: united states research

PUBMED ID PMID:

MEDLINE DATE:

Assessment of health-related quality of life of adolescent cancer patients using the Minneapolis-Manchester Quality of Life Adolescent Questionnaire. Journal Published:

PUBLICATION TYPE: Research Support, N.I.H., Extr

Journal: Pediatric blood & cancer

VOLUME: 48

Page Numbers: 678-86

Journal Abbreviation:

ISSN: 1545-5009

DAY: 15

MONTH: Jun

YEAR: 2007

Assessment of health-related quality of life of adolescent cancer patients using the Minneapolis-Manchester Quality of Life Adolescent Questionnaire. Information

Number of References:

LANGUAGE: eng

NlmUniqueID: 101186624

Assessment of health-related quality of life of adolescent cancer patients using the Minneapolis-Manchester Quality of Life Adolescent Questionnaire. Keywords Mesh Terms:

KEYWORDS: United States

MESH TERMS: therapy

Chemical & Substance for Abstract: Assessment of health-related quality of life of adolescent cancer patients using the Minneapolis-Manchester Quality of Life Adolescent Questionnaire. Information

Substance Name:

Registry Number:

Grant and Affiliation Information for Assessment of health-related quality of life of adolescent cancer patients using the Minneapolis-Manchester Quality of Life Adolescent Questionnaire.

AFFILIATION: Division of Population Sciences, City of Hope National Medical Center, Duarte, California, USA.

Country: United States

AGENCY: United States NCI

GRANT: U10 CA098543

ACRONYM: CA

MEDLINETA: Pediatr Blood Cancer

REFSOURCE:

DATABASENAME:

ACCESSION NUMBER:

Number Hits: 0

Assessment of health-related quality of life of adolescent cancer patients using the Minneapolis-Manchester Quality of Life Adolescent Questionnaire Related Publications

• A simple medium for mounting small insects.
• Antimicrobial susceptibility testing in India - A status survey.
• Aripiprazole therapy for nicotine dependence.
• Assessment of health-related quality of life of adolescent cancer patients using the Minneapolis-Manchester Quality of Life Adolescent Questionnaire.
• Blepharospasm and limb dystonia caused by Mohr-Tranebjaerg syndrome with a novel splice-site mutation in the deafness/dystonia peptide gene.
• Catalytic cracking of palm oil for the production of biofuels: optimization studies.
• Diabetes, hypertension, and cardiovascular events in survivors of hematopoietic cell transplantation: a report from the bone marrow transplantation survivor study.
• Early cardiac development: a Wnt beat away.
• Endogenous hydrogen sulfide regulates leukocyte trafficking in cecal ligation and puncture-induced sepsis.
• Epigenetic regulation of tumor necrosis factor alpha.
• Fluid and electrolyte management in the very low birth weight neonate.
• Health care utilization by adult long-term survivors of hematopoietic cell transplant: report from the Bone Marrow Transplant Survivor Study.
• Hematopoietic development from human embryonic stem cells.
• High-throughput analysis of signals regulating stem cell fate and function.
• Impact factor of Indian Journal of Gastroenterology for the years 2005 and 2006.
• Introduction of newer surgical prostheses and procedures in pelvic reconstruction: a challenge for pelvic surgeons.
• Localized amyloidosis in endometrioid carcinoma of the uterus: a rare association.
• Lower urinary tract dysfunctions in women with diabetes mellitus.
• Methylphenidate-induced akathisia in a patient with multiple sclerosis.
• Micro- to nanoscale structure of biocompatible PLA-PEO-PLA hydrogels.
• Nanoparticle self-assembly gated by logical proteolytic triggers.
• Novel drug release profiles from micellar solutions of PLA-PEO-PLA triblock copolymers.
• Palliative care in the fetus and newborn.
• Proteolytic actuation of nanoparticle self-assembly.
• Role of BCR/ABL gene-expression levels in determining the phenotype and imatinib sensitivity of transformed human hematopoietic cells.
• Role of plaster moulding and padding. Redisplacement of Paediatric forearm fractures.
• Sensitivity index of antimicrobial agents: A new treatment criteria proposed for rational use of antimicrobials.
• Targeted quantum dot conjugates for siRNA delivery.
• The effect of pharmaceuticals on the nanoscale structure of PEO-PPO-PEO micelles.
• [Effect of hypoxia and ischemia on expression of phosphorylated NMDA receptor-1 subunit of cerebral cortex cells]