Assessment of cognitive functioning of methadone-maintenance patients: impact of adult ADHD and current cocaine dependence.

Assessment of cognitive functioning of methadone-maintenance patients: impact of adult ADHD and current cocaine dependence. Research Abstract Details 

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Assessment of cognitive functioning of methadone-maintenance patients: impact of adult ADHD and current cocaine dependence. Abstract Text:

Daniel J Brooks,Suzanne K Vosburg,Suzette M Evans,Frances R Levin,

The purpose of this study was to determine if methadone-maintained patients (MMP) with cocaine dependence (CD) and/or adult Attention Deficit Hyperactivity Disorder (ADHD) exhibited compounded cognitive dysfunction associated with their poly-substance use and/or co-morbid psychiatric diagnoses. The sample consisted of 79 MMP (59% male, 51% Caucasian), maintained on methadone doses ranging from 40-130 mg/day, who were placed into one of four diagnostic categories: (1) a control group (no ADHD, no CD) (n = 24), (2) CD alone (n = 18), (3)ADHDalone (n = 18), and (4)ADHD+ CD(n = 19). The California Computerized Assessment Package (CalCAP) was administered to assess cognitive functioning requiring focused and sustained attention in a standardized fashion. There were no group differences on Simple Reaction tasks. Compared to the control group, the ADHD+ CD group was slower and less accurate on 33% of the Choice Reaction (CR) tasks. Specifically, individuals in the ADHD + CD group and the ADHD alone group performed significantly worse on tasks measuring attention and psychomotor responding. These tasks are associated with broader cognitive skills in working memory, language discrimination and flexibility of cognitive sets that may have implications for treatment outcome. Diagnostic services capable of identifying cognitive deficits among MMP with ADHD and/or CD are needed to maximize the likelihood of treatment success and to serve as an indicator for the efficacy of therapeutic approaches.

Assessment of cognitive functioning of methadone-maintenance patients: impact of adult ADHD and current cocaine dependence. Publishing Authors By Initials

DJ Brooks,SK Vosburg,SM Evans,FR Levin,

For similar investigative techniques: epidemiologic methods: data collection: health surveys: health status indicators: severity of illness index research abstracts see: investigative techniques: epidemiologic methods: data collection: health surveys: health status indicators: severity of illness index research

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Assessment of cognitive functioning of methadone-maintenance patients: impact of adult ADHD and current cocaine dependence. Journal Published:

PUBLICATION TYPE: Research Support, N.I.H., Extr

Journal: Journal of addictive diseases : the official journ

VOLUME: 25

Page Numbers: 15-25

Journal Abbreviation:

ISSN: 1055-0887

DAY: 3

MONTH: 12

YEAR: 2006

Assessment of cognitive functioning of methadone-maintenance patients: impact of adult ADHD and current cocaine dependence. Information

Number of References:

LANGUAGE: eng

NlmUniqueID: 9107051

Assessment of cognitive functioning of methadone-maintenance patients: impact of adult ADHD and current cocaine dependence. Keywords Mesh Terms:

KEYWORDS: Severity of Illness Index

MESH TERMS: therapeutic use

Chemical & Substance for Abstract: Assessment of cognitive functioning of methadone-maintenance patients: impact of adult ADHD and current cocaine dependence. Information

Substance Name: Methadone

Registry Number: 76-99-3

Grant and Affiliation Information for Assessment of cognitive functioning of methadone-maintenance patients: impact of adult ADHD and current cocaine dependence.

AFFILIATION: New York State Psychiatry Institute, Department of Psychiatry, College of Physicians and Surgeons of Columbia University, USA. brooksd@pi.cpmc.columbia.edu

Country: United States

AGENCY: United States PHS

GRANT: K02 00465

ACRONYM: DA

MEDLINETA: J Addict Dis

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