Assessment of adherence to renal dosing guidelines in long-term care facilities.

Assessment of adherence to renal dosing guidelines in long-term care facilities. Research Abstract Details 

Research Abstract Table of Contents

Jump to the:

Assessment of adherence to renal dosing guidelines in long-term care facilities. Abstract Text:

OBJECTIVE: We determined whether dosing guidelines based on creatinine clearance (Ccr) for renally excreted drugs are being applied when prescribing to long-term care residents DESIGN: A cross sectional chart review for the month of May 1999. PARTICIPANTS: Long-term care residents more than 65 years of age from four long-term care facilities in Southern Ontario who were prescribed a medication from a list of renally excreted drugs commonly prescribed in long-term care facilities. RESULTS: Approximately one in three prescriptions (34.1%) were considered inappropriate for the calculated Ccr of the residents. Overall, 42.3% of the residents who were prescribed a drug under review received at least one inappropriate prescription based on creatinine clearance. Logistic regression found that age (odds ratio (OR) = 1.06 per year; 95% confidence interval (CI) 1.03-1.09, P = .001), weight (OR = 0.96 per kg; 95% CI 0.94-0.98, P < .001), the total number of prescribed medications (OR = 1.10; 95% CI 1.04-1.17, P = .001), and the number of physicians prescribing in the facility (OR 1.02; 95% CI, 1.003-1.044, P = .03) were predictive for receiving an inappropriate prescription based on Ccr. CONCLUSIONS: Renal function is often overlooked when prescribing renally excreted drugs to older long-term care residents. These findings emphasize the need for consideration of Ccr when prescribing such drugs in this population.

Assessment of adherence to renal dosing guidelines in long-term care facilities. Publishing Authors By Initials

For similar pharmaceutical preparations research abstracts see: pharmaceutical preparations research

PUBMED ID PMID:

MEDLINE DATE:

Assessment of adherence to renal dosing guidelines in long-term care facilities. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Journal of the American Geriatrics Society

VOLUME: 48

Page Numbers: 1470-3

Journal Abbreviation: J Am Geriatr Soc

ISSN: 0002-8614

DAY: 10

MONTH: Nov

YEAR: 2000

Assessment of adherence to renal dosing guidelines in long-term care facilities. Information

Number of References:

LANGUAGE: eng

NlmUniqueID: 7503062

Assessment of adherence to renal dosing guidelines in long-term care facilities. Keywords Mesh Terms:

KEYWORDS: Pharmaceutical Preparations

MESH TERMS: urine

Chemical & Substance for Abstract: Assessment of adherence to renal dosing guidelines in long-term care facilities. Information

Substance Name: Creatinine

Registry Number: 60-27-5

Grant and Affiliation Information for Assessment of adherence to renal dosing guidelines in long-term care facilities.

AFFILIATION: Department of Medicine, McMaster University, Hamilton, Ontario, Canada.

Country: UNITED STATES

AGENCY:

GRANT:

ACRONYM:

MEDLINETA: J Am Geriatr Soc

REFSOURCE:

DATABASENAME:

ACCESSION NUMBER:

Number Hits: 0

Assessment of adherence to renal dosing guidelines in long-term care facilities Related Publications

• A case study for microbial biodegradation: anaerobic bacterial reductive dechlorination of polychlorinated biphenyls-from sediment to defined medium.
• Artificial exomuscle investigations for applications--metal hydride.
• Assessment of adherence to renal dosing guidelines in long-term care facilities.
• Do chiropractors identify with complementary and alternative medicine? Results of a survey.
• Effect of chronic treatment with (+)-PHNO, a D2 agonist in MPTP-treated monkeys.
• Evaluation of the completeness of reporting of invasive meningococcal disease.
• N-Acetyl-beta-d-Glucosaminidase Index as an Early Biomarker for Chronic Kidney Disease in Cats with Hyperthyroidism.
• NOX enzymes in immuno-inflammatory pathologies.
• Tutorial lecture on weather and acoustics.
• Varicella vaccination for grades 4 and 5 students: from theory to practice.
• [History of Québec sectorial psychiatry.]
• [Not Available.]
• [Not Available.]
• [The prevention of infections in child daycare centers: potential influential factors]