Arrays for the combinatorial exploration of cell adhesion.

Arrays for the combinatorial exploration of cell adhesion. Research Abstract Details 

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Arrays for the combinatorial exploration of cell adhesion. Abstract Text:

Brendan P Orner,Ratmir Derda,Rachel L Lewis,James A Thomson,Laura L Kiessling,

A new method for the fabrication of arrays of self-assembled monolayers (SAMs) of alkane thiols (ATs) on gold to combinatorially assay surfaces for cell adhesion is reported. A fluorous SAM, which is both cytophobic and solvophobic, was used as the background between the array features. The resulting solvophobic background permits the application of an assembly after conjugation strategy for fabrication. SAMs containing mixtures of ATs and peptide-terminated ATs were generated. Multiple cell types demonstrated differential and specific binding to these surfaces. Additionally, pluripotent human embryonic stem cells proliferated on surfaces generated by this method.

Arrays for the combinatorial exploration of cell adhesion. Publishing Authors By Initials

BP Orner,R Derda,RL Lewis,JA Thomson,LL Kiessling,

For similar cells: cells, cultured: cell line: 3t3 cells: swiss 3t3 cells research abstracts see: cells: cells, cultured: cell line: 3t3 cells: swiss 3t3 cells research

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Arrays for the combinatorial exploration of cell adhesion. Journal Published:

PUBLICATION TYPE: Research Support, U.S. Gov't,

Journal: Journal of the American Chemical Society

VOLUME: 126

Page Numbers: 10808-9

Journal Abbreviation: J. Am. Chem. Soc.

ISSN: 0002-7863

DAY: 8

MONTH: Sep

YEAR: 2004

Arrays for the combinatorial exploration of cell adhesion. Information

Number of References:

LANGUAGE: eng

NlmUniqueID: 7503056

Arrays for the combinatorial exploration of cell adhesion. Keywords Mesh Terms:

KEYWORDS: Swiss 3T3 Cells

MESH TERMS: chemistry

Chemical & Substance for Abstract: Arrays for the combinatorial exploration of cell adhesion. Information

Substance Name: arginyl-glycyl-aspartic acid

Registry Number: 99896-85-2

Grant and Affiliation Information for Arrays for the combinatorial exploration of cell adhesion.

AFFILIATION: Department of Biochemistry, University of Wisconsin, Madison, WI 53706, USA.

Country: United States

AGENCY: United States NIA

GRANT: AG 19550

ACRONYM: AG

MEDLINETA: J Am Chem Soc

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