Argyrophil cell carcinoma (apudoma) of the esophagus. A histopathologic entity.

Argyrophil cell carcinoma (apudoma) of the esophagus. A histopathologic entity. Research Abstract Details 

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Argyrophil cell carcinoma (apudoma) of the esophagus. A histopathologic entity. Abstract Text:

R Tateishi,K Taniguchi,T Horai,T Iwanaga,H Taniguchi,

In a series of 79 cases of primary esophageal carcinoma resected at The Center for Adult Diseases, Osaka, there were six tumors with specific histopathologic features valid for the diagnosis of argyrophil cell carcinoma. Of the 6 tumors, 3 were studied electron microscopically and assay for ACTH content was performed on 4 tumors. Clinically, the ages of the 6 patients ranged from 56 to 71 years; two were women and four men. Four of the 6 patients died with widespread tumor recurrences within 9 months of operation. Microscopically, the 6 tumors were composed largely or almost entirely of small, spindle-shaped cells resembling those of oat cell carcinoma of the lung, and were characterized by the arrangement of tumor cells in solid sheets or anastomosing cords, the presence of argyrophil tumor cells, and the deposits of amyloid. Electron microscopically, the three tumors contained neurosecretory-type granules. Using bioassay or radioimmunoassay ACTH activity in the tumor tissues was detected in 3 out of the 4 tumors determined. From the light and electron microscopic characteristics and the assay evidence, it seems reasonable to conclude that the 6 tumors are endocrine polypeptide producing tumors (apudomas) that arise from argyrophil cells normally found among the basal cells of the esophageal mucosa, and that they represent a distinct histopathologic entity clearly distinguishable from other types of esophageal carcinomas.

Argyrophil cell carcinoma (apudoma) of the esophagus. A histopathologic entity. Publishing Authors By Initials

R Tateishi,K Taniguchi,T Horai,T Iwanaga,H Taniguchi,

For similar endocrine system: neurosecretory systems research abstracts see: endocrine system: neurosecretory systems research

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Argyrophil cell carcinoma (apudoma) of the esophagus. A histopathologic entity. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Virchows Archiv. A, Pathological anatomy and histo

VOLUME: 371

Page Numbers: 283-94

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ISSN: 0340-1227

DAY: 7

MONTH: Oct

YEAR: 1976

Argyrophil cell carcinoma (apudoma) of the esophagus. A histopathologic entity. Information

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LANGUAGE: eng

NlmUniqueID: 7505137

Argyrophil cell carcinoma (apudoma) of the esophagus. A histopathologic entity. Keywords Mesh Terms:

KEYWORDS: Neurosecretory Systems

MESH TERMS: cytology

Chemical & Substance for Abstract: Argyrophil cell carcinoma (apudoma) of the esophagus. A histopathologic entity. Information

Substance Name: Adrenocorticotropic Hormone

Registry Number: 9002-60-2

Grant and Affiliation Information for Argyrophil cell carcinoma (apudoma) of the esophagus. A histopathologic entity.

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Country: GERMANY, WEST

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MEDLINETA: Virchows Arch A Pathol Anat Hi

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