Application of DNA microarray technology to gerontological studies.

Application of DNA microarray technology to gerontological studies. Research Abstract Details 

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Application of DNA microarray technology to gerontological studies. Abstract Text:

Sergey V Anisimov,

The emergence of microarray technology as a novel tool in molecular biology has led to significant progress in many biomedical disciplines, including gerontology. Both cDNA and oligonucleotide-based DNA microarrays are now widely used to identify the basic physiological mechanisms of aging and to uncover the molecular mechanisms underlying the biological effects of anti-aging drugs. Two different protocols covering both cDNA and oligonucleotide microarray platforms, with radioactive and nonradioactive (fluorescent) labeling, are detailed in the manuscript. These in-depth protocols provide a background for the technical aspects of everyday work with DNA microarrays.

Application of DNA microarray technology to gerontological studies. Publishing Authors By Initials

SV Anisimov,

For similar investigative techniques: chemistry, analytical: microchip analytical procedures: microarray analysis: oligonucleotide array sequence analysis research abstracts see: investigative techniques: chemistry, analytical: microchip analytical procedures: microarray analysis: oligonucleotide array sequence analysis research

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Application of DNA microarray technology to gerontological studies. Journal Published:

PUBLICATION TYPE: Review

Journal: Methods in molecular biology (Clifton, N.J.)

VOLUME: 371

Page Numbers: 249-65

Journal Abbreviation: Methods Mol. Biol.

ISSN: 1064-3745

DAY: 3

MONTH: 12

YEAR: 2007

Application of DNA microarray technology to gerontological studies. Information

Number of References: 20

LANGUAGE: eng

NlmUniqueID: 9214969

Application of DNA microarray technology to gerontological studies. Keywords Mesh Terms:

KEYWORDS: Oligonucleotide Array Sequence Analysis

MESH TERMS: methods

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Grant and Affiliation Information for Application of DNA microarray technology to gerontological studies.

AFFILIATION: Neuronal Survival Unit, Wallenberg Neuroscience Center, Lund University, Lund, Sweden.

Country: United States

AGENCY: United States NINDS

GRANT: 1 R21 NS043717-01A1

ACRONYM: NS

MEDLINETA: Methods Mol Biol

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