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[Application of cryopreserved allograft to aortic root replacement for valve detachment case due to aortitis]

[Application of cryopreserved allograft to aortic root replacement for valve detachment case due to aortitis] Research Abstract Details 

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  • [Application of cryopreserved allograft to aortic root replacement for valve detachment case due to aortitis] Abstract Text:

    n motomuraN Motomura,k kawazoeK Kawazoe,h kitoH Kito,k eishiK Eishi,y kawashimaY Kawashima,t okaT Oka,

    A 54-year-old male who had received an aortic valve replacement with SJM 23 about 3 years before suffered from an acute cardiac failure because of the valve detachment. From his clinical course, it was diagnosed that the aortic valve insufficiency was complicated by an aortitis. We operated on him by an aortic root replacement using a cryopreserved allograft which we prepared. A donor of the allograft was 35-year-old male, died of a subarachnoidal hemorrhage. We harvested his aortic root at an autopsy and dipped it into a nutrition medium with 10% dimethylsulfoxide. Within 10 hours from his death, we froze the tissue using a program freezer and stored it in a liquid nitrogen for 7 months. After thawing it in 37 degrees C water quickly, we rinsed the graft and used for the operation. The cell viability of the graft was confirmed by a tissue culture. Indication of the allograft valve to an aortitis case is still controversial. We think the allograft is recommendable to valve detachment case due to aortitis, because the softness of the graft decreases a compliance mismatch between the graft and the patient's annulus, which may prevent redetachment. Although we felt concern about redetachment of the conduit due to the weakness of the patient's aortic annulus, no complication regarding the allograft happened at all as yet.

    [Application of cryopreserved allograft to aortic root replacement for valve detachment case due to aortitis] Publishing Authors By Initials

    n motomuraN Motomura,k kawazoeK Kawazoe,h kitoH Kito,k eishiK Eishi,y kawashimaY Kawashima,t okaT Oka,

    For similar surgical procedures, operative: reoperation research abstracts see: surgical procedures, operative: reoperation research

    PUBMED ID PMID:

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    [Application of cryopreserved allograft to aortic root replacement for valve detachment case due to aortitis] Journal Published:

    PUBLICATION TYPE: Journal Article

    Journal: [Zasshi] [Journal]. Nihon Ky?bu Geka Gakkai

    VOLUME: 41

    Page Numbers: 1426-30

    Journal Abbreviation:

    ISSN: 0369-4739

    DAY: 14

    MONTH: Aug

    YEAR: 1993

    [Application of cryopreserved allograft to aortic root replacement for valve detachment case due to aortitis] Information

    Number of References:

    LANGUAGE: jpn

    NlmUniqueID: 19130180

    [Application of cryopreserved allograft to aortic root replacement for valve detachment case due to aortitis] Keywords Mesh Terms:

    KEYWORDS: Reoperation

    MESH TERMS: surgery

    Chemical & Substance for Abstract: [Application of cryopreserved allograft to aortic root replacement for valve detachment case due to aortitis] Information

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    Grant and Affiliation Information for [Application of cryopreserved allograft to aortic root replacement for valve detachment case due to aortitis]

    AFFILIATION: Department of Cardiovascular Surgery, National Cardiovascular Center, Osaka, Japan.

    Country: JAPAN

    JAPAN Research PublicationJAPAN Research Publication

    AGENCY:

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    MEDLINETA: Nippon Kyobu Geka Gakkai Zassh

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