Apolipoprotein A-II: a protein in search of a function.

Apolipoprotein A-II: a protein in search of a function. Research Abstract Details 

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Apolipoprotein A-II: a protein in search of a function. Abstract Text:

C C Hedrick,A J Lusis,

OBJECTIVE: To summarize current findings relevant to the function of apolipoprotein A-II (apoA-II), a major protein component of high density lipoproteins (HDL). STUDY SELECTION: Studies relating to the structure, regulation and genetics of apoA-II are reviewed. These include studies of apoA-II expression in humans and mouse animal models. All studies cited were published between 1972 and 1993. CONCLUSIONS: Since its discovery over 20 years ago, apoA-II has been a protein in search of a function. In fact, it has often been stated that apoA-II has no major function in plasma lipoprotein metabolism. While it is clear that apoA-II does not serve an essential function in HDL metabolism, the evidence overwhelmingly indicates that apoA-II importantly influences HDL functional states and suggests strongly that apoA-II is likely to contribute to atherogenesis.

Apolipoprotein A-II: a protein in search of a function. Publishing Authors By Initials

CC Hedrick,AJ Lusis,

For similar animals: chordata: vertebrates: mammals: primates: haplorhini: catarrhini: hominidae: humans research abstracts see: animals: chordata: vertebrates: mammals: primates: haplorhini: catarrhini: hominidae: humans research

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Apolipoprotein A-II: a protein in search of a function. Journal Published:

PUBLICATION TYPE: Review

Journal: The Canadian journal of cardiology

VOLUME: 10

Page Numbers: 453-9

Journal Abbreviation:

ISSN: 1916-7075

DAY: 3

MONTH: May

YEAR: 1994

Apolipoprotein A-II: a protein in search of a function. Information

Number of References: 67

LANGUAGE: eng

NlmUniqueID: 8510280

Apolipoprotein A-II: a protein in search of a function. Keywords Mesh Terms:

KEYWORDS: Humans

MESH TERMS: physiopathology

Chemical & Substance for Abstract: Apolipoprotein A-II: a protein in search of a function. Information

Substance Name: Apolipoprotein A-II

Registry Number: 0

Grant and Affiliation Information for Apolipoprotein A-II: a protein in search of a function.

AFFILIATION: Department of Medicine, University of California, Los Angeles.

Country: CANADA

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MEDLINETA: Can J Cardiol

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