Antiproliferative xanthones of Terminalia calcicola from the Madagascar rain forest.

Antiproliferative xanthones of Terminalia calcicola from the Madagascar rain forest. Research Abstract Details 

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Antiproliferative xanthones of Terminalia calcicola from the Madagascar rain forest. Abstract Text:

Shugeng Cao,Peggy J Brodie,James S Miller,Richard Randrianaivo,Fidy Ratovoson,Chris Birkinshaw,Rabodo Andriantsiferana,Vincent E Rasamison,David G I Kingston,

A bioassay-guided fractionation of the EtOH extract of the Madagascan plant Terminalia calcicola led to the isolation of two new cytotoxic xanthones, termicalcicolanone A (1) and termicalcicolanone B (2). The structures of the new compounds were established on the basis of one- and two-dimensional NMR spectroscopic data. Both compounds showed modest antiproliferative activity toward the A2780 human ovarian cancer cell line.

Antiproliferative xanthones of Terminalia calcicola from the Madagascar rain forest. Publishing Authors By Initials

S Cao,PJ Brodie,JS Miller,R Randrianaivo,F Ratovoson,C Birkinshaw,R Andriantsiferana,VE Rasamison,DG Kingston,

For similar heterocyclic compounds: heterocyclic compounds, 3-ring: xanthenes: xanthones research abstracts see: heterocyclic compounds: heterocyclic compounds, 3-ring: xanthenes: xanthones research

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MEDLINE DATE:

Antiproliferative xanthones of Terminalia calcicola from the Madagascar rain forest. Journal Published:

PUBLICATION TYPE: Research Support, U.S. Gov't,

Journal: Journal of natural products

VOLUME: 70

Page Numbers: 679-81

Journal Abbreviation:

ISSN: 0163-3864

DAY: 27

MONTH: 02

YEAR: 2007

Antiproliferative xanthones of Terminalia calcicola from the Madagascar rain forest. Information

Number of References:

LANGUAGE: eng

NlmUniqueID: 7906882

Antiproliferative xanthones of Terminalia calcicola from the Madagascar rain forest. Keywords Mesh Terms:

KEYWORDS: Xanthones

MESH TERMS: pharmacology

Chemical & Substance for Abstract: Antiproliferative xanthones of Terminalia calcicola from the Madagascar rain forest. Information

Substance Name: termicalcicolanone B

Registry Number: 0

Grant and Affiliation Information for Antiproliferative xanthones of Terminalia calcicola from the Madagascar rain forest.

AFFILIATION: Department of Chemistry, M/C 0212, Virginia Polytechnic Institute and State University, Blacksburg, Virginia 24061, USA.

Country: United States

AGENCY: United States FIC

GRANT: U01 TW000313

ACRONYM: TW

MEDLINETA: J Nat Prod

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