Antiproliferative Cassane Diterpenoids of Cordyla madagascariensis ssp. madagascariensis from the Madagascar Rainforest(1).

Antiproliferative Cassane Diterpenoids of Cordyla madagascariensis ssp. madagascariensis from the Madagascar Rainforest(1). Research Abstract Details 

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Antiproliferative Cassane Diterpenoids of Cordyla madagascariensis ssp. madagascariensis from the Madagascar Rainforest(1). Abstract Text:

Yanpeng Hou,Shugeng Cao,Peggy Brodie,James S Miller,Chris Birkinshaw,Fidisoa Ratovoson,Roland Rakotondrajaona,Rabodo Andriantsiferana,Vincent E Rasamison,David G I Kingston,Yanpeng Hou,Shugeng Cao,Peggy Brodie,James S Miller,Chris Birkinshaw,Fidisoa Ratovoson,Roland Rakotondrajaona,Rabodo Andriantsiferana,Vincent E Rasamison,David G I Kingston,

Bioassay-guided fractionation of an ethanol extract of a Madagascar collection of the fruits of Cordyla madagascariensis ssp. madagascariensis led to the isolation of the four new cassane diterpenoids 1- 4. The (1)H and (13)C NMR spectra of all compounds were fully assigned using a combination of 2D NMR experiments, including COSY, HSQC, HMBC, and ROESY sequences. All of the isolates were tested against the A2780 human ovarian cancer cell line, and compounds 1 and 2 showed mild antiproliferative activity with IC 50 values of 10 and 36 microM, respectively.

Antiproliferative Cassane Diterpenoids of Cordyla madagascariensis ssp. madagascariensis from the Madagascar Rainforest(1). Publishing Authors By Initials

Y Hou,S Cao,P Brodie,JS Miller,C Birkinshaw,F Ratovoson,R Rakotondrajaona,R Andriantsiferana,VE Rasamison,DG Kingston,Y Hou,S Cao,P Brodie,JS Miller,C Birkinshaw,F Ratovoson,R Rakotondrajaona,R Andriantsiferana,VE Rasamison,DG Kingston,

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Antiproliferative Cassane Diterpenoids of Cordyla madagascariensis ssp. madagascariensis from the Madagascar Rainforest(1). Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Journal of natural products

VOLUME: 71

Page Numbers: 150-2

Journal Abbreviation: J. Nat. Prod.

ISSN: 0163-3864

DAY: 29

MONTH: 12

YEAR: 2007

Antiproliferative Cassane Diterpenoids of Cordyla madagascariensis ssp. madagascariensis from the Madagascar Rainforest(1). Information

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LANGUAGE: eng

NlmUniqueID: 7906882

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AFFILIATION: dkingston@vt.edu.

Country: United States

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MEDLINETA: J Nat Prod

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