Antinociceptive, anti-inflammatory and antipyretic properties of the aqueous extract of Bauhinia purpurea leaves in experimental animals.

Antinociceptive, anti-inflammatory and antipyretic properties of the aqueous extract of Bauhinia purpurea leaves in experimental animals. Research Abstract Details 

Research Abstract Table of Contents

Jump to the:

Antinociceptive, anti-inflammatory and antipyretic properties of the aqueous extract of Bauhinia purpurea leaves in experimental animals. Abstract Text:

Zainul Amiruddin Zakaria,Loo Yi Wen,Nurul Izzah Abdul Rahman,Abdul Halim Abdul Ayub,Mohd Roslan Sulaiman,Hanan Kumar Gopalan,Zainul Amiruddin Zakaria,Loo Yi Wen,Nurul Izzah Abdul Rahman,Abdul Halim Abdul Ayub,Mohd Roslan Sulaiman,Hanan Kumar Gopalan,

OBJECTIVE: The present study was carried out to determine the antinociceptive, anti-inflammatory and antipyretic activities of the aqueous extract of Bauhinia purpurea leaves using animal models. MATERIALS AND METHODS: The air-dried, powdered leaves (approximately 20 g) were soaked in distilled water (1:20; w/v) at room temperature for 72 h and the supernatant obtained was freeze-dried. The crude dried extract (approximately 2.4 g) was prepared in doses of 6.0, 30.0 and 60.0 mg/kg, and subjected to the respective antinociceptive (abdominal constriction, hot plate and formalin tests), anti-inflammatory (carrageenan-induced paw edema test) and antipyretic (brewer's yeast-induced pyrexia test) assays. RESULTS:The results obtained indicate that the extract possessed significant (p < 0.05) antinociceptive, anti-inflammatory and antipyretic activities, which were not dependent on the doses of extract used. The highest concentration of extract was less effective as an anti-inflammatory and an antipyretic agent. CONCLUSION: This study showed that the aqueous extract of B. purpurea leaves possesses potential pharmacological activities that require further investigation and, thus, confirms the folklore use of the plant in the treatment of ailments associated with pain and inflammation.

Antinociceptive, anti-inflammatory and antipyretic properties of the aqueous extract of Bauhinia purpurea leaves in experimental animals. Publishing Authors By Initials

ZA Zakaria,LY Wen,NI Abdul Rahman,AH Abdul Ayub,MR Sulaiman,HK Gopalan,ZA Zakaria,LY Wen,NI Abdul Rahman,AH Abdul Ayub,MR Sulaiman,HK Gopalan,

For similar animals: chordata: vertebrates: mammals: rodentia: muridae: murinae: rats: rats, sprague-dawley research abstracts see: animals: chordata: vertebrates: mammals: rodentia: muridae: murinae: rats: rats, sprague-dawley research

PUBMED ID PMID:

MEDLINE DATE:

Antinociceptive, anti-inflammatory and antipyretic properties of the aqueous extract of Bauhinia purpurea leaves in experimental animals. Journal Published:

PUBLICATION TYPE: Research Support, Non-U.S. Gov

Journal: Medical principles and practice : international jo

VOLUME: 16

Page Numbers: 443-9

Journal Abbreviation:

ISSN: 1423-0151

DAY: 20

MONTH: 11

YEAR: 2007

Antinociceptive, anti-inflammatory and antipyretic properties of the aqueous extract of Bauhinia purpurea leaves in experimental animals. Information

Number of References:

LANGUAGE: eng

NlmUniqueID: 8901334

Antinociceptive, anti-inflammatory and antipyretic properties of the aqueous extract of Bauhinia purpurea leaves in experimental animals. Keywords Mesh Terms:

KEYWORDS: Rats, Sprague-Dawley

MESH TERMS: therapeutic use

Chemical & Substance for Abstract: Antinociceptive, anti-inflammatory and antipyretic properties of the aqueous extract of Bauhinia purpurea leaves in experimental animals. Information

Substance Name: Plant Extracts

Registry Number: 0

Grant and Affiliation Information for Antinociceptive, anti-inflammatory and antipyretic properties of the aqueous extract of Bauhinia purpurea leaves in experimental animals.

AFFILIATION: Faculty of Pharmacy, Universiti Teknologi Mara, Shah Alam, Selangor, Malaysia. shaza8174@yahoo.com

Country: Switzerland

AGENCY:

GRANT:

ACRONYM:

MEDLINETA: Med Princ Pract

REFSOURCE:

DATABASENAME:

ACCESSION NUMBER:

Number Hits: 0

Antinociceptive, anti-inflammatory and antipyretic properties of the aqueous extract of Bauhinia purpurea leaves in experimental animals Related Publications

• A multidirectional non-cell autonomous control and a genetic interaction restricting tobacco etch virus susceptibility in Arabidopsis.
• Antidiuretic factor in the urines of patients with nutritional oedema.
• Antinociceptive, anti-inflammatory and antipyretic properties of the aqueous extract of Bauhinia purpurea leaves in experimental animals.
• Antizyme1 mediates AURKAIP1-dependent degradation of Aurora-A.
• Downregulation of Aurora-A overrides estrogen-mediated growth and chemoresistance in breast cancer cells.
• EFFECT OF FEEDING AFLATOXIN TO YOUNG MONKEYS.
• Magnetic color symmetry of lattice rotations in a diamagnetic material.
• Malnutrition in childhood in the tropics.
• Polymeric brushes as functional templates for immobilizing ribonuclease a: study of binding kinetics and activity.
• Self-assembly directed synthesis of poly(ortho-toluidine)-metal(gold and palladium) composite nanospheres.
• Studies on Methanocaldococcus jannaschii RNase P reveal insights into the roles of RNA and protein cofactors in RNase P catalysis.
• Studies on the mechanism of inhibition of bacterial ribonuclease P by aminoglycoside derivatives.
• Three-dimensional grain boundary spectroscopy in transparent high power ceramic laser materials.