Antidote stocking in British Columbia hospitals.

Antidote stocking in British Columbia hospitals. Research Abstract Details 

Research Abstract Table of Contents

Jump to the:

Antidote stocking in British Columbia hospitals. Abstract Text:

Sean K Gorman,Peter J Zed,Roy A Purssell,Jeffrey Brubacher,Gillian A Willis,

INTRODUCTION: Previous studies have demonstrated that antidotes are insufficiently stocked in Canadian and US health care facilities. The purpose of this study was to determine the adequacy of antidote stocking in British Columbia hospitals based on the current guidelines. METHODS: A written survey was mailed to hospital pharmacy directors at all 93 acute care facilities in BC. Availability of 14 essential antidotes was classified as sufficient or insufficient based on the current guidelines. Facilities were stratified into small (<50 beds), medium (50-250 beds) or large (>250 beds); teaching or non-teaching; trauma or non-trauma, urban or rural, and isolated or non-isolated. RESULTS: Complete responses were received from 75 (81%) of 93 hospitals. No hospital had adequate stock of all 14 antidotes. Overall, the average number (+/- standard deviation) of antidotes adequately stocked was 4.2 +/- 2.9 per hospital. Urban hospitals had adequate stocks of 6.5 +/- 2.6 antidotes while rural centres had adequate stocks of 2.6 +/- 1.8 (p < 0.001). Corresponding figures were 9.0 +/- 1.8 for teaching hospitals vs. 3.7 +/- 2.4 for non-teaching hospitals (p < 0.001), 8.9 +/- 2.0 for trauma centres vs. 3.8 +/- 2.5 non-trauma centres (p < 0.001), and 2.5 +/- 2.1 for isolated hospitals vs. 4.6 +/- 2.9 for non-isolated hospitals (p = 0.018). Small, medium, and large hospitals adequately stocked 2.3 +/- 1.7, 5.7 +/- 2.2, and 7.7 +/- 3.0 antidotes, respectively (p < 0.001). The 4 antidotes most adequately stocked were sodium bicarbonate (77%), N-acetylcysteine (64%), ethanol (49%) and naloxone (47%). Digoxin immune Fab fragments, glucagon, pyridoxine and rattlesnake antivenin were poorly stocked with sufficient supplies of 5%, 7%, 7% and 13%, respectively. CONCLUSION: BC hospitals do not have adequate antidote stocks. Provincial stocking guidelines and coordination of antidote purchasing and stocking are necessary to correct these deficiencies.

Antidote stocking in British Columbia hospitals. Publishing Authors By Initials

SK Gorman,PJ Zed,RA Purssell,J Brubacher,GA Willis,

For similar abstracts research abstracts see: abstracts research

PUBMED ID PMID:

MEDLINE DATE:

Antidote stocking in British Columbia hospitals. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: CJEM : Canadian journal of emergency medical care

VOLUME: 5

Page Numbers: 12-7

Journal Abbreviation:

ISSN: 1481-8035

DAY: 30

MONTH: Jan

YEAR: 2003

Antidote stocking in British Columbia hospitals. Information

Number of References:

LANGUAGE: eng

NlmUniqueID: 100893237

Antidote stocking in British Columbia hospitals. Keywords Mesh Terms:

KEYWORDS:

MESH TERMS:

Chemical & Substance for Abstract: Antidote stocking in British Columbia hospitals. Information

Substance Name:

Registry Number:

Grant and Affiliation Information for Antidote stocking in British Columbia hospitals.

AFFILIATION: CSU Pharmaceutical Sciences, Vancouver General Hospital, Vancouver, British Columbia, Canada.

Country: Canada

AGENCY:

GRANT:

ACRONYM:

MEDLINETA: CJEM

REFSOURCE:

DATABASENAME:

ACCESSION NUMBER:

Number Hits: 0

Antidote stocking in British Columbia hospitals Related Publications

• A 38-year-old Hispanic woman with paradoxical embolism and Libman-Sacks endocarditis involving the tricuspid valve.
• Activation of protein kinase B/Akt in the periphery contributes to pain behavior induced by capsaicin in rats.
• Age group and health status effects on health behavior change.
• An energy-based body temperature threshold between torpor and normothermia for small mammals.
• Antidote stocking in British Columbia hospitals.
• Base-promoted reactions of dichlorocarbene adducts of cyclic enamines: a new route to annulated pyrroles.
• CPF and CPFL, two related gene families encoding cuticular proteins of Anopheles gambiae and other insects.
• Discovery of Potent and Selective Adamantane-Based Small-Molecule P2X(7) Receptor Antagonists/Interleukin-1beta Inhibitors.
• Drosophila cuticular proteins with the R&R Consensus: annotation and classification with a new tool for discriminating RR-1 and RR-2 sequences.
• Endothelin-1 induces alveolar epithelial-mesenchymal transition through endothelin type A receptor-mediated production of TGF-beta1.
• Factors associated with positive screens on the mood disorder questionnaire in primary care.
• Fluorescence of putative chromophores in Skh-1 and citrate-soluble calf skin collagens.
• From ATP to AZD6140: the discovery of an orally active reversible P2Y12 receptor antagonist for the prevention of thrombosis.
• Identification of internal ribosome entry segment (IRES)-trans-acting factors for the Myc family of IRESs.
• Intradermal injection of capsaicin induces acute substance P release from rat spinal cord dorsal horn.
• Intramolecular palladium-catalyzed direct arylation of alkenyl triflates.
• Nitric oxide attenuates epithelial-mesenchymal transition in alveolar epithelial cells.
• Octahedral and trigonal prismatic structure preferences in a bicyclic hexaamine cage for zinc(II), cadmium(II) and mercury(II) ions.
• Odor-modulated Navigation in Insects and Artificial Systems.
• Palladium-catalysed N-annulation routes to indoles: the synthesis of indoles with sterically demanding N-substituents, including demethylasterriquinone A1.
• Proteomic analysis of cast cuticles from Anopheles gambiae by tandem mass spectrometry.
• Pulmonary tuberculosis in pregnancy.
• Re-programming of translation following cell stress allows IRES-mediated translation to predominate.
• Sensorimotor control of navigation in arthropod and artificial systems.
• Site-selective modification of peptides using rhodium and palladium catalysis: complementary electrophilic and nucleophilic arylation.
• Studies on Lagenophrys tattersalli (Ciliata, Peritricha, Vorticellinae) observations on bionomics, conjugation, and apparent endomixis.
• The bitter end: the ubiquitin-proteasome system and cardiac dysfunction.
• The somatosensory system, with emphasis on structures important for pain.
• Total syntheses of tambjamines C, E, F, G, H, I and J, BE-18591, and a related alkaloid from the marine bacterium Pseudoalteromonas tunicata.
• UN Declaration on the Rights of Indigenous Peoples.