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Antibody response to whole cells and teichoic acid of Staphylococcus aureus strain E 1369 in human sera.

Antibody response to whole cells and teichoic acid of Staphylococcus aureus strain E 1369 in human sera. Research Abstract Details 

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  • Antibody response to whole cells and teichoic acid of Staphylococcus aureus strain E 1369 in human sera. Abstract Text:

    j o jarløvJ O Jarløv,f espersenF Espersen,b christenssonB Christensson,b a jensenB A Jensen,s a hedströmS A Hedström,j b hertzJ B Hertz,

    A whole cell Staphylococcus aureus enzyme-linked immunosorbent assay (ELISA) using the protein A-deficient strain E 1369 as antigen was compared to an ELISA with cell-wall teichoic acid, extracted from the same strain, as antigen for the detection of IgG antibodies against S. aureus in human sera. A total of 178 serum samples from 119 patients with S. aureus endocarditis, complicated and uncomplicated septicaemia, non-S. aureus endocarditis and septicaemia were investigated together with sera from 155 healthy controls. The sensitivity in diagnosing S. aureus endocarditis was better for the whole cell-ELISA (83%) as compared to the teichoic acid-ELISA (61%), and the same was true for complicated septicaemia (41% vs 29%). The whole cell ELISA was also more specific for S. aureus infections with only 3.6% false positive test values compared to 7.1% for the teichoic acid-ELISA. The differences were however, not statistically significant. None of the assays were able to distinguish between complicated and uncomplicated S. aureus septicaemia.

    Antibody response to whole cells and teichoic acid of Staphylococcus aureus strain E 1369 in human sera. Publishing Authors By Initials

    jo jarløvJO Jarløv,f espersenF Espersen,b christenssonB Christensson,ba jensenBA Jensen,sa hedströmSA Hedström,jb hertzJB Hertz,

    For similar carbohydrates: glycosides: teichoic acids research abstracts see: carbohydrates: glycosides: teichoic acids research

    PUBMED ID PMID:

    MEDLINE DATE:

    Antibody response to whole cells and teichoic acid of Staphylococcus aureus strain E 1369 in human sera. Journal Published:

    PUBLICATION TYPE: Journal Article

    Journal: Acta pathologica, microbiologica, et immunologica

    VOLUME: 95

    Page Numbers: 115-20

    Journal Abbreviation:

    ISSN: 0108-0180

    DAY: 12

    MONTH: Apr

    YEAR: 1987

    Antibody response to whole cells and teichoic acid of Staphylococcus aureus strain E 1369 in human sera. Information

    Number of References:

    LANGUAGE: eng

    NlmUniqueID: 8206623

    Antibody response to whole cells and teichoic acid of Staphylococcus aureus strain E 1369 in human sera. Keywords Mesh Terms:

    KEYWORDS: Teichoic Acids

    MESH TERMS: immunology

    Chemical & Substance for Abstract: Antibody response to whole cells and teichoic acid of Staphylococcus aureus strain E 1369 in human sera. Information

    Substance Name: Teichoic Acids

    Registry Number: 0

    Grant and Affiliation Information for Antibody response to whole cells and teichoic acid of Staphylococcus aureus strain E 1369 in human sera.

    AFFILIATION:

    Country: DENMARK

    DENMARK Research PublicationDENMARK Research Publication

    AGENCY:

    GRANT:

    ACRONYM:

    MEDLINETA: Acta Pathol Microbiol Immunol

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