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Anti-inflammatory mechanisms of dietary restriction in slowing aging processes.

Anti-inflammatory mechanisms of dietary restriction in slowing aging processes. Research Abstract Details 

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  • Anti-inflammatory mechanisms of dietary restriction in slowing aging processes. Abstract Text:

    t e morganT E Morgan,a m wongA M Wong,c e finchC E Finch,

    Dietary restriction (DR) remains the most powerful and general environmental manipulation of aging processes in laboratory animals with strong beneficial effects on most age-related degenerative changes throughout the body. Underlying the beneficial effects of DR is the attenuation of system-wide inflammatory processes including those occurring within the central nervous system. During normal aging a progressive neuroinflammatory state builds in the brain involving astrocytes and microglia, the primary cellular components of neuroinflammation. DR attenuates the age-related activation of astrocytes and microglia with concomitant beneficial effects on neurodegeneration and cognition. Increasing evidence suggests that common pathways are emerging that link many normal aging inflammatory processes with age-related diseases such as Alzheimer, cancer, diabetes and cardiovascular disease.

    Anti-inflammatory mechanisms of dietary restriction in slowing aging processes. Publishing Authors By Initials

    te morganTE Morgan,am wongAM Wong,ce finchCE Finch,

    For similar abstracts research abstracts see: abstracts research

    PUBMED ID PMID:

    MEDLINE DATE:

    Anti-inflammatory mechanisms of dietary restriction in slowing aging processes. Journal Published:

    PUBLICATION TYPE: Review

    Journal: Interdisciplinary topics in gerontology

    VOLUME: 35

    Page Numbers: 83-97

    Journal Abbreviation:

    ISSN: 0074-1132

    DAY: 3

    MONTH: 12

    YEAR: 2007

    Anti-inflammatory mechanisms of dietary restriction in slowing aging processes. Information

    Number of References:

    LANGUAGE: eng

    NlmUniqueID: 135125

    Anti-inflammatory mechanisms of dietary restriction in slowing aging processes. Keywords Mesh Terms:

    KEYWORDS: Peroxisome Proliferator-Activated Recept

    MESH TERMS: physiology

    Chemical & Substance for Abstract: Anti-inflammatory mechanisms of dietary restriction in slowing aging processes. Information

    Substance Name: Glucose

    Registry Number: 50-99-7

    Grant and Affiliation Information for Anti-inflammatory mechanisms of dietary restriction in slowing aging processes.

    AFFILIATION: Leonard Davis School of Gerontology and USC College, University of Southern California, 3715 McClintock Avenue, Los Angeles, CA 90089, USA. temorgan@usc.edu

    Country: Switzerland

    Switzerland Research PublicationSwitzerland Research Publication

    AGENCY: United States NIA

    GRANT: AG 13499

    ACRONYM: AG

    MEDLINETA: Interdiscip Top Gerontol

    REFSOURCE:

    DATABASENAME:

    ACCESSION NUMBER:

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